MPA43/YNL249C Protein Information

Standard Name	Mpa43p 1
Systematic Name	Ynl249cp
ORF Classification	Verified
Description	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (2, 3)
Name Description	Multicopy PDC1 Activator

Experimental Data
Molecules/cell	1050 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	542
Molecular Weight (Da)	61,667
Isoelectric Point (pI)	6.51

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mpa43p (InterPro)
Physical Interactions	There are 7 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012F42C \| P53583 MIPS: YNL249C NCBI: 1122899 \| 1255969 \| 1302291 \| 1709083 \| 51830504 \| 6324080 \| NP_014150.1 GenBank/EMBL/DDBJ: DAA10310.1 \| AY723861 \| X94214 \| X96722 \| Z71525

Amino Acid Sequence (or in FASTA format)
1 MNSSLQVGIG IDVGSSSARI GVYNYYNDAL LEMAQEPVPY YQDSSKKSWK 51 FWQKSTEIIK ALQKCLQKLN IREYEVKSCG VSATCSLAIF ERDRTSNMLI 101 PYPNEDNVIF WMDSSAVNEC QWLNMQCPQQ LLDYLGGKFV PEMGVPKLKY 151 FLDEYSHLRD KHFHIFDLHQ YIAYELSRLY EWNIEGLLGR ENLNGIGNDG 201 EVSGWSSSFY KNIINLPSNV SIGTTSLVAN KHISTTVVRS CIDSYASWFA 251 VASPHLETSL FMIAGTSSCY MYGTTISDTR IPGVWGPFDT ILDNRGDFSV 301 YAAGQSCTGK LIEHLFESHP CARKILKDGA DIYQVLEQTI RDIEKNNGLS 351 IHILTKDMFF YGDYEGNRTP FADPRIKGSF IGESTDTSML NLTYKYICIL 401 EFLSFQTKLI IDTFQNENSN IHIKELRISG SQAKNERLLS LISLVNNGVA 451 IIKPKENVDM MGIKGAYVLA KSAKEKKQLA DVITERDISN DSEKFESLAE 501 YRLGNDSILL RKLLCVKYHI HLDMAKQQKR YHKLVDEVFQ HL*

Amino Acid Sequence (or in FASTA format)

       1  MNSSLQVGIG IDVGSSSARI GVYNYYNDAL LEMAQEPVPY YQDSSKKSWK
      51  FWQKSTEIIK ALQKCLQKLN IREYEVKSCG VSATCSLAIF ERDRTSNMLI
     101  PYPNEDNVIF WMDSSAVNEC QWLNMQCPQQ LLDYLGGKFV PEMGVPKLKY
     151  FLDEYSHLRD KHFHIFDLHQ YIAYELSRLY EWNIEGLLGR ENLNGIGNDG
     201  EVSGWSSSFY KNIINLPSNV SIGTTSLVAN KHISTTVVRS CIDSYASWFA
     251  VASPHLETSL FMIAGTSSCY MYGTTISDTR IPGVWGPFDT ILDNRGDFSV
     301  YAAGQSCTGK LIEHLFESHP CARKILKDGA DIYQVLEQTI RDIEKNNGLS
     351  IHILTKDMFF YGDYEGNRTP FADPRIKGSF IGESTDTSML NLTYKYICIL
     401  EFLSFQTKLI IDTFQNENSN IHIKELRISG SQAKNERLLS LISLVNNGVA
     451  IIKPKENVDM MGIKGAYVLA KSAKEKKQLA DVITERDISN DSEKFESLAE
     501  YRLGNDSILL RKLLCVKYHI HLDMAKQQKR YHKLVDEVFQ HL*

external links for Mpa43p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Mpa43p

1)	Boles, E., et al. (1995) S. cerevisiae MPA43 Gene. Unpublished
2)	Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
3)	Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41