SPS19/YNL202W Protein Information

Standard Name	Sps19p
Systematic Name	Ynl202wp
Alias	Spx19p
ORF Classification	Verified
Description	Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate (1, 2)
Name Description	SPorulation Specific transcript
Gene Product	2,4-dienoyl-CoA reductase 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	292
Molecular Weight (Da)	31,109
Isoelectric Point (pI)	9.67

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Sps19p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000D796A3 \| P32573 MIPS: YNL202W NCBI: 110279051 \| 1302205 \| 51013689 \| 553143 \| 600063 \| 730864 \| 99030931 \| NP_014197.2 GenBank/EMBL/DDBJ: DAA10352.1 \| AY693119 \| M90351 \| X78898 \| Z71479
External Classifications	EC: 1.3.1.34 [2,4-dienoyl-CoA reductase (NADPH)]

Amino Acid Sequence (or in FASTA format)
1 MNTANTLDGK FVTEGSWRPD LFKGKVAFVT GGAGTICRVQ TEALVLLGCK 51 AAIVGRDQER TEQAAKGISQ LAKDKDAVLA IANVDVRNFE QVENAVKKTV 101 EKFGKIDFVI AGAAGNFVCD FANLSPNAFK SVVDIDLLGS FNTAKACLKE 151 LKKSKGSILF VSATFHYYGV PFQGHVGAAK AGIDALAKNL AVELGPLGIR 201 SNCIAPGAID NTEGLKRLAG KKYKEKALAK IPLQRLGSTR DIAESTVYIF 251 SPAASYVTGT VLVVDGGMWH LGTYFGHELY PEALIKSMTS KL*

Amino Acid Sequence (or in FASTA format)

       1  MNTANTLDGK FVTEGSWRPD LFKGKVAFVT GGAGTICRVQ TEALVLLGCK
      51  AAIVGRDQER TEQAAKGISQ LAKDKDAVLA IANVDVRNFE QVENAVKKTV
     101  EKFGKIDFVI AGAAGNFVCD FANLSPNAFK SVVDIDLLGS FNTAKACLKE
     151  LKKSKGSILF VSATFHYYGV PFQGHVGAAK AGIDALAKNL AVELGPLGIR
     201  SNCIAPGAID NTEGLKRLAG KKYKEKALAK IPLQRLGSTR DIAESTVYIF
     251  SPAASYVTGT VLVVDGGMWH LGTYFGHELY PEALIKSMTS KL*

external links for Sps19p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Sps19p

1)	Gurvitz A, et al. (1997) The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19. J Biol Chem 272(35):22140-7
2)	Coe JG, et al. (1994) Identification of a sporulation-specific promoter regulating divergent transcription of two novel sporulation genes in Saccharomyces cerevisiae. Mol Gen Genet 244(6):661-72