ESBP6/YNL125C Protein Information

Standard Name	Esbp6p
Systematic Name	Ynl125cp
Alias	Mch3p
ORF Classification	Verified
Description	Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane (1)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	673
Molecular Weight (Da)	73,801
Isoelectric Point (pI)	8.38

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Esbp6p (InterPro)
Transmembrane Domains	There are 11 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 21 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BB7A \| P53918 MIPS: YNL125C NCBI: 1183945 \| 1302058 \| 1730773 \| 6324204 \| 695732 \| 861115 \| NP_014274.1 GenBank/EMBL/DDBJ: DAA10424.1 \| X84903 \| Z46843 \| Z69382 \| Z71401

Amino Acid Sequence (or in FASTA format)
1 MSTHSNDYFS ASSGMVSETS SEVSSINSSQ PVSFSKASIA APVPCSDLHS 51 TKSNDASRKL SISRTLTNRL NDIKKAVDDD NLQTEENSAD VNKILESRFD 101 VADAIRLQHN ESVQSKLNIP VTHTTTAGAS LSAPSSSAFS ASSIQNDTTE 151 HKASMDSKLM RNRLYPASTK HSGKDLEAQG ITEFEPDEPT VKKVFTNKST 201 GQLELPPDGG YGWVVTFCVF LTMFSTWGCN ASFGVDLAYY LNHDTYPGAS 251 KYDYALIAGL TVFLGQLLSP LVMALMRIIG LRTTMLFGDA VMLAAYLLAS 301 FTTKLWQLYV TQGFMVGCSI SLIFVPATTV LPGWFLKKRA VAMGVSLLGT 351 GAGGVVYGLA TNKMLSDFGN TRWCLRIIGI SCSISVLVAI ALLKERNPTP 401 AIGLKSPRAM FEQLKAMFSL KVITKPFVVL IALWFMFALF AYNMMVFTLS 451 SYAISKGLSS HDASTLTAIL NGSQSIGRPL MGLAGDKFGR ANVTIVLTTL 501 LTIYMFAFWI PAHTFVQLIF FSILVGSCVG VANVMNTVLI ADMVKPEEFL 551 PAWAFVNYCG APFLLVCEVI AQALTVEKDK SNPYLHAQIF CGCCFIAALI 601 LISILREYSI RMKLTERQAM TNEKLKEWKA SEYDTDSADE DWGKLKERKT 651 KYDLLLGPGI KKYFLRMVYP MKV*

Amino Acid Sequence (or in FASTA format)

       1  MSTHSNDYFS ASSGMVSETS SEVSSINSSQ PVSFSKASIA APVPCSDLHS
      51  TKSNDASRKL SISRTLTNRL NDIKKAVDDD NLQTEENSAD VNKILESRFD
     101  VADAIRLQHN ESVQSKLNIP VTHTTTAGAS LSAPSSSAFS ASSIQNDTTE
     151  HKASMDSKLM RNRLYPASTK HSGKDLEAQG ITEFEPDEPT VKKVFTNKST
     201  GQLELPPDGG YGWVVTFCVF LTMFSTWGCN ASFGVDLAYY LNHDTYPGAS
     251  KYDYALIAGL TVFLGQLLSP LVMALMRIIG LRTTMLFGDA VMLAAYLLAS
     301  FTTKLWQLYV TQGFMVGCSI SLIFVPATTV LPGWFLKKRA VAMGVSLLGT
     351  GAGGVVYGLA TNKMLSDFGN TRWCLRIIGI SCSISVLVAI ALLKERNPTP
     401  AIGLKSPRAM FEQLKAMFSL KVITKPFVVL IALWFMFALF AYNMMVFTLS
     451  SYAISKGLSS HDASTLTAIL NGSQSIGRPL MGLAGDKFGR ANVTIVLTTL
     501  LTIYMFAFWI PAHTFVQLIF FSILVGSCVG VANVMNTVLI ADMVKPEEFL
     551  PAWAFVNYCG APFLLVCEVI AQALTVEKDK SNPYLHAQIF CGCCFIAALI
     601  LISILREYSI RMKLTERQAM TNEKLKEWKA SEYDTDSADE DWGKLKERKT
     651  KYDLLLGPGI KKYFLRMVYP MKV*

external links for Esbp6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Esbp6p

1)	Makuc J, et al. (2001) The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Yeast 18(12):1131-43