MTQ1/YNL063W Protein Information

Standard Name	Mtq1p 1
Systematic Name	Ynl063wp
ORF Classification	Verified
Description	S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene (1)
Name Description	Methyltransferase 1

Experimental Data
Molecules/cell	13200 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	314
Molecular Weight (Da)	35,870
Isoelectric Point (pI)	10.18

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mtq1p (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BB39 \| P53944 MIPS: YNL063W NCBI: 1301939 \| 1730740 \| 51012621 \| 6324266 \| 994824 \| NP_014336.1 GenBank/EMBL/DDBJ: DAA10483.1 \| AY692585 \| U12141 \| Z71339
External Classifications	EC: 2.1.1.- [Transferases transferring one-carbon groups methyltransferases]

Amino Acid Sequence (or in FASTA format)
1 MPRISTSLIR KASRIRPGLH LLLPECRTLE QAKLEYKWLT EELPPDKSIR 51 WACLQRYKHV PLQYILRSQP FGALDIVCKP GVLIPRWETE EWVMAIIRAL 101 NNSMLSRHTI PLHICDTFTG TGCIALALSH GIANCTFTAI DVSTRAIKLV 151 KENMLKNKVS GGKLVQHNIL SSKASDEYPS HIDILTGNPP YIRKRDFNRD 201 VKTSVKLFEP RLALVGELEC YINLVNYWLP KTDSFFYEIG DVEQFNYVER 251 RIKEDSYLSR IWSIGLKYDS NGKARVVYGF KATPKGRILH QIFASFGTIR 301 HLATALSGHK ANCN*

Amino Acid Sequence (or in FASTA format)

       1  MPRISTSLIR KASRIRPGLH LLLPECRTLE QAKLEYKWLT EELPPDKSIR
      51  WACLQRYKHV PLQYILRSQP FGALDIVCKP GVLIPRWETE EWVMAIIRAL
     101  NNSMLSRHTI PLHICDTFTG TGCIALALSH GIANCTFTAI DVSTRAIKLV
     151  KENMLKNKVS GGKLVQHNIL SSKASDEYPS HIDILTGNPP YIRKRDFNRD
     201  VKTSVKLFEP RLALVGELEC YINLVNYWLP KTDSFFYEIG DVEQFNYVER
     251  RIKEDSYLSR IWSIGLKYDS NGKARVVYGF KATPKGRILH QIFASFGTIR
     301  HLATALSGHK ANCN*

external links for Mtq1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Mtq1p

1)	Polevoda B, et al. (2006) The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p. J Biol Chem 281(5):2562-71
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41