HHF2/YNL030W Protein Information 
| Standard Name | Hhf2p |
|---|---|
| Systematic Name | Ynl030wp |
| ORF Classification | Verified |
| Description | Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity (1, 2, 3, 4, 5, 6) |
| Name Description | Histone H Four |
| Experimental Data | |
|---|---|
| Molecules/cell | 681000 7 |
| Click on image for expanded interactive view |
|---|
| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Hhf2p (InterPro) |
| Physical Interactions | There are 536 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI000004F8D3 | P02309 MIPS: YNL030W NCBI: 11513448 | 119389631 | 122107 | 1301868 | 158430380 | 158430382 | 15988133 | 15988137 | 162329885 | 162329886 | 171639 | 326327711 | 356624623 | 3756 | 3759 | 50513648 | 50513650 | 51013371 | 536202 | 6319481 | 6324298 | NP_009563.1 | NP_014368.1 GenBank/EMBL/DDBJ: DAA07130.1 | DAA10515.1 | AY692960 | K03154 | X00724 | X00725 | Z35878 | Z71306 |
external links for Hhf2p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | YPL+ |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YeastGFP |
| Aspergillus (AspGD) | BioPIXIE | MIPS | YeastRC Public Image Repository |
| Candida (CGD) | CYC2008 (complexes) | Pfam domains | |
| Candida (CGD) | Complexome | YeastRC Structure Prediction (Seattle) | |
| Candida (CandidaDB) | DIP | ||
| Candida (CandidaDB) | GeneMANIA | ||
| YGOB | YeastRC Mass Spec (Seattle) | ||
| YOGY |
References cited on this page View Complete Literature Guide for Hhf2p
| 1) | Megee PC, et al. (1995) Histone H4 and the maintenance of genome integrity. Genes Dev 9(14):1716-27 |
| 2) | Wyrick JJ, et al. (1999) Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature 402(6760):418-21 |
| 3) | Smith MM, et al. (1996) A novel histone H4 mutant defective in nuclear division and mitotic chromosome transmission. Mol Cell Biol 16(3):1017-26 |
| 4) | Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 |
| 5) | Grunstein M (1990) Histone function in transcription. Annu Rev Cell Biol 6:643-78 |
| 6) | Altheim BA and Schultz MC (1999) Histone modification governs the cell cycle regulation of a replication-independent chromatin assembly pathway in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(4):1345-50 |
| 7) | Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41 |
