YNL024C Protein Information

Systematic Name	Ynl024cp
ORF Classification	Uncharacterized
Description	Putative methyltransferase; has seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; despite similarity to methyltransferases, null mutant does not display alterations in lysine methylation pattern (1, 2, 3, 4)

Experimental Data
Molecules/cell	1760 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	246
Molecular Weight (Da)	27,738
Isoelectric Point (pI)	6.18

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ynl024cp (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BAF1 \| P53970 MIPS: YNL024C NCBI: 1301857 \| 1730714 \| 6324304 \| NP_014374.1 GenBank/EMBL/DDBJ: DAA10521.1 \| Z71300

Amino Acid Sequence (or in FASTA format)
1 MESIFGGFGD LVVPRPKEHL GQTDLSFGGK LLPALKICED GGESGCGGKV 51 WIAGELLCEY ILEKSVDHLL SKTVNGTKQF KKVLELGSGT GLVGLCVGLL 101 EKNTFHDGTK VYVTDIDKLI PLLKRNIELD EVQYEVLARE LWWGEPLSAD 151 FSPQEGAMQA NNVDLVLAAD CVYLEEAFPL LEKTLLDLTH CINPPVILMA 201 YKKRRKADKH FFNKIKRNFD VLEITDFSKF EHYLKERTHL FQLIRK*

Amino Acid Sequence (or in FASTA format)

       1  MESIFGGFGD LVVPRPKEHL GQTDLSFGGK LLPALKICED GGESGCGGKV
      51  WIAGELLCEY ILEKSVDHLL SKTVNGTKQF KKVLELGSGT GLVGLCVGLL
     101  EKNTFHDGTK VYVTDIDKLI PLLKRNIELD EVQYEVLARE LWWGEPLSAD
     151  FSPQEGAMQA NNVDLVLAAD CVYLEEAFPL LEKTLLDLTH CINPPVILMA
     201  YKKRRKADKH FFNKIKRNFD VLEITDFSKF EHYLKERTHL FQLIRK*

external links for Ynl024cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ynl024cp

1)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2)	Katz JE, et al. (2003) Automated identification of putative methyltransferases from genomic open reading frames. Mol Cell Proteomics 2(8):525-40
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Couttas TA, et al. (2012) Methylation of translation-associated proteins in Saccharomyces cerevisiae: Identification of methylated lysines and their methyltransferases. Proteomics 12(7):960-72
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41