RLP7/YNL002C Protein Information Help

Standard Name Rlp7p 1
Systematic Name Ynl002cp
Alias Rpl7p
ORF Classification Verified
Description Nucleolar protein similar to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs; binds junction of ITS2 and ITS2-proximal stem between the 3' end of 5.8S rRNA and the 5' end of 25S rRNA (1, 2, 3, 4)
Name Description Ribosomal-Like Protein 1
Experimental Data
Molecules/cell 7720 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 322
Molecular Weight (Da) 36,559
Isoelectric Point (pI) 10.24

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rlp7p (InterPro)
Physical Interactions There are 456 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000053117 | P40693
MIPS: YNL002C
NCBI: 1301814 | 398365527 | 450647 | 496712 | 51013513 | 730570 | NP_014396.3 | NM_001182841.3
GenBank/EMBL/DDBJ: AAA34982.1 | AAT93050.1 | CAA54376.1 | CAA95861.1 | DAA10541.1 | AY693031 | L19167 | X77114 | Z71278
Amino Acid Sequence (or in FASTA format)
       1  MSSTQDSKAQ TLNSNPEILL RKRRNADRTR IERQELAKKK REEQIKKKRS
      51  NKNKFVRAES IVAKTLATSR EKERIKRVSI LEDKKAKNET QHIASGKDFI
     101  LKITEKANGA EENSVDLEET EEEEDDGLIR EKTTYDGKPA LLFIVRVRGP
     151  LAVNIPNKAF KILSLLRLVE TNTGVFVKLT KNVYPLLKVI APYVVIGKPS
     201  LSSIRSLIQK RGRIIYKGEN EAEPHEIVLN DNNIVEEQLG DHGIICVEDI
     251  IHEIATMGES FSVCNFFLQP FKLNREVSGF GSLNRLRKIK QREAESRTRQ
     301  FSNAATAPVI EVDIDSLLAK LN*                             

external links for Rlp7p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains YeastRC Public Image Repository
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Rlp7p
1) Lalo D, et al.  (1993) Two distinct yeast proteins are related to the mammalian ribosomal polypeptide L7. Yeast 9(10):1085-91
2) Dunbar DA, et al.  (2000) A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proc Natl Acad Sci U S A 97(24):13027-32
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
4) Dembowski JA, et al.  (2013) Identification of the binding site of Rlp7 on assembling 60S ribosomal subunits in Saccharomyces cerevisiae. RNA 19(12):1639-47
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41