ERR3/YMR323W Protein Information

Standard Name	Err3p 1
Systematic Name	Ymr323wp
ORF Classification	Verified
Description	Enolase, a phosphopyruvate hydratase; catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate; complements the growth defect of an ENO1 ENO2 double mutant in glucose (1, 2)
Name Description	Enolase-Related Repeat 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	437
Molecular Weight (Da)	47,312
Isoelectric Point (pI)	5.19

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Err3p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012A17E \| P42222 MIPS: YMR323W NCBI: 1072413 \| 1706698 \| 398366127 \| NP_014056.3 GenBank/EMBL/DDBJ: DAA10224.1 \| Z54141
External Classifications	EC: 4.2.1.11 [Phosphopyruvate hydratase]

Amino Acid Sequence (or in FASTA format)
1 MSITKVHART VYDSRGNPTV EVEITTENGL FRAIVPSGAS TGIHEAVELR 51 DGNKSEWMGK GVTKAVSNVN SIIGPALIKS DLCVTNQKGI DELMISLDGT 101 SNKSRLGANA ILGVSLCVAR AAAAQKGITL YKYIAELADA RQDPFVIPVP 151 FFNVLNGGAH AGGSLAMQEF KIAPVGAQSF AEAMRMGSEV YHHLKILAKE 201 QYGPSAGNVG DEGGVAPDID TAEDALDMIV KAINICGYEG RVKVGIDSAP 251 SVFYKDGKYD LNFKEPNSDP SHWLSPAQLA EYYHSLLKKY PIISLEDPYA 301 EDDWSSWSAF LKTVNVQIIA DDLTCTNKTR IARAIEEKCA NTLLLKLNQI 351 GTLTESIEAA NQAFDAGWGV MISHRSGETE DPFIADLVVG LRCGQIKSGA 401 LSRSERLAKY NELLRIEEEL GDDCIYAGHR FHDGNKL*

Amino Acid Sequence (or in FASTA format)

       1  MSITKVHART VYDSRGNPTV EVEITTENGL FRAIVPSGAS TGIHEAVELR
      51  DGNKSEWMGK GVTKAVSNVN SIIGPALIKS DLCVTNQKGI DELMISLDGT
     101  SNKSRLGANA ILGVSLCVAR AAAAQKGITL YKYIAELADA RQDPFVIPVP
     151  FFNVLNGGAH AGGSLAMQEF KIAPVGAQSF AEAMRMGSEV YHHLKILAKE
     201  QYGPSAGNVG DEGGVAPDID TAEDALDMIV KAINICGYEG RVKVGIDSAP
     251  SVFYKDGKYD LNFKEPNSDP SHWLSPAQLA EYYHSLLKKY PIISLEDPYA
     301  EDDWSSWSAF LKTVNVQIIA DDLTCTNKTR IARAIEEKCA NTLLLKLNQI
     351  GTLTESIEAA NQAFDAGWGV MISHRSGETE DPFIADLVVG LRCGQIKSGA
     401  LSRSERLAKY NELLRIEEEL GDDCIYAGHR FHDGNKL*

external links for Err3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Err3p

1)	Pryde FE, et al. (1995) Sequence analysis of the right end of chromosome XV in Saccharomyces cerevisiae: an insight into the structural and functional significance of sub-telomeric repeat sequences. Yeast 11(4):371-82
2)	Kornblatt MJ, et al. (2013) The Saccharomyces cerevisiae enolase-related regions encode proteins that are active enolases. Yeast 30(2):55-69