ADH2/YMR303C Protein Information

Standard Name	Adh2p 1
Systematic Name	Ymr303cp
Alias	Adr2p
ORF Classification	Verified
Description	Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1 (2, 3, 4)
Name Description	Alcohol DeHydrogenase

Experimental Data
Molecules/cell	1620 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	348
Molecular Weight (Da)	36,732
Isoelectric Point (pI)	6.72

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Adh2p (InterPro)
Physical Interactions	There are 23 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001683EA \| P00331 MIPS: YMR303C NCBI: 113380 \| 171021 \| 171029 \| 6323961 \| 798945 \| NP_014032.1 GenBank/EMBL/DDBJ: DAA10204.1 \| J01314 \| M38457 \| Z49212
External Classifications	EC: 1.1.1.1 [Alcohol dehydrogenase] EC: 1.1.1.190 [Indole-3-acetaldehyde reductase (NADH)]

Amino Acid Sequence (or in FASTA format)
1 MSIPETQKAI IFYESNGKLE HKDIPVPKPK PNELLINVKY SGVCHTDLHA 51 WHGDWPLPTK LPLVGGHEGA GVVVGMGENV KGWKIGDYAG IKWLNGSCMA 101 CEYCELGNES NCPHADLSGY THDGSFQEYA TADAVQAAHI PQGTDLAEVA 151 PILCAGITVY KALKSANLRA GHWAAISGAA GGLGSLAVQY AKAMGYRVLG 201 IDGGPGKEEL FTSLGGEVFI DFTKEKDIVS AVVKATNGGA HGIINVSVSE 251 AAIEASTRYC RANGTVVLVG LPAGAKCSSD VFNHVVKSIS IVGSYVGNRA 301 DTREALDFFA RGLVKSPIKV VGLSSLPEIY EKMEKGQIAG RYVVDTSK*

Amino Acid Sequence (or in FASTA format)

       1  MSIPETQKAI IFYESNGKLE HKDIPVPKPK PNELLINVKY SGVCHTDLHA
      51  WHGDWPLPTK LPLVGGHEGA GVVVGMGENV KGWKIGDYAG IKWLNGSCMA
     101  CEYCELGNES NCPHADLSGY THDGSFQEYA TADAVQAAHI PQGTDLAEVA
     151  PILCAGITVY KALKSANLRA GHWAAISGAA GGLGSLAVQY AKAMGYRVLG
     201  IDGGPGKEEL FTSLGGEVFI DFTKEKDIVS AVVKATNGGA HGIINVSVSE
     251  AAIEASTRYC RANGTVVLVG LPAGAKCSSD VFNHVVKSIS IVGSYVGNRA
     301  DTREALDFFA RGLVKSPIKV VGLSSLPEIY EKMEKGQIAG RYVVDTSK*

external links for Adh2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Mass Spec (Seattle)
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Adh2p

1)	Ciriacy, M. (1985) Personal Communication, Mortimer Map Edition 9
2)	Young ET and Pilgrim D (1985) Isolation and DNA sequence of ADH3, a nuclear gene encoding the mitochondrial isozyme of alcohol dehydrogenase in Saccharomyces cerevisiae. Mol Cell Biol 5(11):3024-34
3)	Bennetzen JL and Hall BD (1982) The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase. J Biol Chem 257(6):3018-25
4)	Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41