JNM1/YMR294W Protein Information

Standard Name	Jnm1p 1
Systematic Name	Ymr294wp
Alias	Ins1p , Pac3p 2
ORF Classification	Verified
Description	Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B (1, 3)
Name Description	Just Nuclear Migration 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	373
Molecular Weight (Da)	43,607
Isoelectric Point (pI)	4.66

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Jnm1p (InterPro)
Physical Interactions	There are 55 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012DABC \| P36224 MIPS: YMR294W NCBI: 1708584 \| 437918 \| 530351 \| 6323951 \| NP_014022.1 GenBank/EMBL/DDBJ: DAA10195.1 \| X80836 \| Z25750

Amino Acid Sequence (or in FASTA format)
1 MNVIDLSDPA INVDYDSLIG IDNEESQEIF ENEVKEDGQQ EEQEEASSRK 51 DGLIVEPGRD VESLRRAIRD QLLFKIHRQN QSDCADARKL SNDEEDESRQ 101 QKLERIREEL EELKIENLTS EMQTEIKELC EIQSKLATES SSRLTNLRKK 151 LLETYEGQDT VILPNIILDT SNIKRLQKLD QKISLMERFV GIPEALEAEE 201 DRKSVHSKVN ELYRSIQLLQ GDDKAEGKLQ KFRDRLVELN EEFENSLLGK 251 KIQQDLRLKD DTVSKLVMPE NKVKEINSMY SMFKQYQDSL PLLAERMKSL 301 NKMNNRVIEV YETTKGLDSQ ITSIQEQGKV WLKALNELDK KFDEQEVKIR 351 ENMEQIRRKI DTLEDEALQR NSK*

Amino Acid Sequence (or in FASTA format)

       1  MNVIDLSDPA INVDYDSLIG IDNEESQEIF ENEVKEDGQQ EEQEEASSRK
      51  DGLIVEPGRD VESLRRAIRD QLLFKIHRQN QSDCADARKL SNDEEDESRQ
     101  QKLERIREEL EELKIENLTS EMQTEIKELC EIQSKLATES SSRLTNLRKK
     151  LLETYEGQDT VILPNIILDT SNIKRLQKLD QKISLMERFV GIPEALEAEE
     201  DRKSVHSKVN ELYRSIQLLQ GDDKAEGKLQ KFRDRLVELN EEFENSLLGK
     251  KIQQDLRLKD DTVSKLVMPE NKVKEINSMY SMFKQYQDSL PLLAERMKSL
     301  NKMNNRVIEV YETTKGLDSQ ITSIQEQGKV WLKALNELDK KFDEQEVKIR
     351  ENMEQIRRKI DTLEDEALQR NSK*

external links for Jnm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Jnm1p

1)	McMillan JN and Tatchell K (1994) The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle. J Cell Biol 125(1):143-58
2)	Geiser JR, et al. (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8(6):1035-50
3)	Kahana JA, et al. (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell 9(7):1741-56