YMR279C Protein Information Help

Systematic Name Ymr279cp
ORF Classification Verified
Description Putative boron transporter involved in boron efflux and resistance; overexpression mutant but not null mutant displays boron tolerance phenotype; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene; YMR279C has a paralog, ATR1, that arose from the whole genome duplication (1, 2, 3, 4)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 540
Molecular Weight (Da) 59,561
Isoelectric Point (pI) 8.22

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ymr279cp (InterPro)
Transmembrane Domains There are 13 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 7 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B942 | Q03263
MIPS: YMR279C
NCBI: 2501165 | 6323935 | 825545 | NP_014006.1
GenBank/EMBL/DDBJ: DAA10180.1 | Z49704
External Classifications TC: 2.A.1.3 [The Drug:H+ Antiporter-2 (14 Spanner) (DHA2) Family]
Amino Acid Sequence (or in FASTA format)
 
       1  MFSIFKKKTS VQGTDSEIDE KITVKAKDKV VVSTEDEEVT TIVSSTKSTQ
      51  VTNDSPWQDP TYFSSFGKEL MFIATCMLAQ LLNQAGQTHA LCIMNVLSKS
     101  FNSEANNQAW LMASFPLAAG SFILISGRLG DIYGLKKMLI VGYVIVIVWS
     151  IISGLSKYSN SDAFFITSRA FQGVGIAFIL PNIMGLVGHV YKVGSFRKNI
     201  VISFIGACAP TGGMFGGLFG GLIVTEDPNQ WPWVFYAFGI ATFLSLLMAW
     251  YSIPNNVPTN IHGLSMDWTG SALAIIGLIL FNFVWNQAPI VGWDKPYIIV
     301  LLIISVIFLV AFFVYESKYA EVPLLPRAMT KNRHMIMILL AVFLGWGSFG
     351  IWTFYYVSFQ LNLRHYSPVW TGGTYFVFVI FGSMAAFFVA FSIKRLGPAL
     401  LLCFSLMAFD AGSIMFSVLP VEQSYWKLNF AMQAILCFGM DLSFPASSII
     451  LSDGLPMQYQ GMAGSLVNTV INYSASLCLG MGGTVEHQIN KSGNDLLKGY
     501  RAAVYLGVGL ASLGVVISVT YMLENLWNRH RKSEDRSLEA *

external links for Ymr279cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome TCDB

DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Ymr279cp
1) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
2) Sakaki K, et al.  (2003) Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. J Biochem 134(3):373-84
3) Kaya A, et al.  (2009) Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Mol Cell Biol 29(13):3665-74
4) Bozdag GO, et al.  (2011) Roles of ATR1 paralogs YMR279c and YOR378w in boron stress tolerance. Biochem Biophys Res Commun 409(4):748-51