YMR226C Protein Information

Systematic Name	Ymr226cp
ORF Classification	Verified
Description	NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments (1, 2, 3)

Experimental Data
Molecules/cell	3210 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	267
Molecular Weight (Da)	29,158
Isoelectric Point (pI)	6.81

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ymr226cp (InterPro)
Physical Interactions	There are 14 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B91D \| Q05016 MIPS: YMR226C NCBI: 2492763 \| 334359534 \| 334359535 \| 334359536 \| 334359537 \| 6323882 \| 887607 \| NP_013953.1 \| NM_001182733.1 GenBank/EMBL/DDBJ: DAA10125.1 \| Z49939
External Classifications	EC: 1.-.-.- [Oxidoreductases]

Amino Acid Sequence (or in FASTA format)
1 MSQGRKAAER LAKKTVLITG ASAGIGKATA LEYLEASNGD MKLILAARRL 51 EKLEELKKTI DQEFPNAKVH VAQLDITQAE KIKPFIENLP QEFKDIDILV 101 NNAGKALGSD RVGQIATEDI QDVFDTNVTA LINITQAVLP IFQAKNSGDI 151 VNLGSIAGRD AYPTGSIYCA SKFAVGAFTD SLRKELINTK IRVILIAPGL 201 VETEFSLVRY RGNEEQAKNV YKDTTPLMAD DVADLIVYAT SRKQNTVIAD 251 TLIFPTNQAS PHHIFRG*

Amino Acid Sequence (or in FASTA format)

       1  MSQGRKAAER LAKKTVLITG ASAGIGKATA LEYLEASNGD MKLILAARRL
      51  EKLEELKKTI DQEFPNAKVH VAQLDITQAE KIKPFIENLP QEFKDIDILV
     101  NNAGKALGSD RVGQIATEDI QDVFDTNVTA LINITQAVLP IFQAKNSGDI
     151  VNLGSIAGRD AYPTGSIYCA SKFAVGAFTD SLRKELINTK IRVILIAPGL
     201  VETEFSLVRY RGNEEQAKNV YKDTTPLMAD DVADLIVYAT SRKQNTVIAD
     251  TLIFPTNQAS PHHIFRG*

external links for Ymr226cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ymr226cp

1)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2)	Fujisawa H, et al. (2003) Characterization of short-chain dehydrogenase/reductase homologues of Escherichia coli (YdfG) and Saccharomyces cerevisiae (YMR226C). Biochim Biophys Acta 1645(1):89-94
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41