INP2/YMR163C Protein Information

Standard Name	Inp2p 1
Systematic Name	Ymr163cp
ORF Classification	Verified
Description	Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene (1)
Name Description	INheritance of Peroxisomes 1

Experimental Data
Molecules/cell	736 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	705
Molecular Weight (Da)	81,466
Isoelectric Point (pI)	9.41

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Inp2p (InterPro)
Physical Interactions	There are 11 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000053238 \| Q03824 MIPS: YMR163C NCBI: 2497169 \| 6323815 \| 825568 \| NP_013886.1 GenBank/EMBL/DDBJ: DAA10059.1 \| Z49705

Amino Acid Sequence (or in FASTA format)
1 MTTNSRPSAL QAPGLQIFSM LKSSEEDGFM SSSLTLDSDN IIGVTENNRQ 51 EFYSTWRKPS LLSSRSVLHE YSPTIVGSND CTFSPITVGK TTKFFNWDDI 101 ISRIFMQQPF GVTHQFFEEF RYSIITSHFL NDMNHYRLSL HLDQSIMNFH 151 KSSTLLKNVP PKSVPFMATK YGKLAVAEDK KLYFRQNFNY LSMIITSYRV 201 LTQLKKYCRK KNSPGLKRVV ILILVAVYLS IQQEYFRRHL ICYKTLLKVR 251 KVLESLQQVD VMIHKYHLRF KEIKNHSFIS RVSLISIADE HSSVIKELLV 301 FSSDALFYKL KSIIPDIVIF SDTSELSKYC ELYGIDVPNL YYNNTTTVKD 351 LDGKLYRLKL LKKFMLCCLL SLDMTGNENL SNVNMRNALN KIFPDYMARV 401 QLKKKYNPIG TFQNIVSLLR GLHSLLSTVL VSLNDHKQIL YAFPEETSTN 451 TGCERANVCS FSKNDKLFQA LNYLKMIENN LLAIDIRNGI TENDRNIIED 501 KLEELITFWK TSKICGNISR IQKVSPTNTI NHGFHLDILK GRKSPRSSSV 551 QGLSLERKVD FIDVAESVND SFENDTELEE YEDYDCQEEC SAGSRQNHRV 601 DFIGKDSCRK PDFKQLSDNE LRRKLDERIL KLAQENREGR ERLRTAKSFE 651 LLRKAQASMS VKFGFQKPLR DDAFLESRPL SKCKVSSEET IPFLYELKGL 701 LGNDS*

Amino Acid Sequence (or in FASTA format)

       1  MTTNSRPSAL QAPGLQIFSM LKSSEEDGFM SSSLTLDSDN IIGVTENNRQ
      51  EFYSTWRKPS LLSSRSVLHE YSPTIVGSND CTFSPITVGK TTKFFNWDDI
     101  ISRIFMQQPF GVTHQFFEEF RYSIITSHFL NDMNHYRLSL HLDQSIMNFH
     151  KSSTLLKNVP PKSVPFMATK YGKLAVAEDK KLYFRQNFNY LSMIITSYRV
     201  LTQLKKYCRK KNSPGLKRVV ILILVAVYLS IQQEYFRRHL ICYKTLLKVR
     251  KVLESLQQVD VMIHKYHLRF KEIKNHSFIS RVSLISIADE HSSVIKELLV
     301  FSSDALFYKL KSIIPDIVIF SDTSELSKYC ELYGIDVPNL YYNNTTTVKD
     351  LDGKLYRLKL LKKFMLCCLL SLDMTGNENL SNVNMRNALN KIFPDYMARV
     401  QLKKKYNPIG TFQNIVSLLR GLHSLLSTVL VSLNDHKQIL YAFPEETSTN
     451  TGCERANVCS FSKNDKLFQA LNYLKMIENN LLAIDIRNGI TENDRNIIED
     501  KLEELITFWK TSKICGNISR IQKVSPTNTI NHGFHLDILK GRKSPRSSSV
     551  QGLSLERKVD FIDVAESVND SFENDTELEE YEDYDCQEEC SAGSRQNHRV
     601  DFIGKDSCRK PDFKQLSDNE LRRKLDERIL KLAQENREGR ERLRTAKSFE
     651  LLRKAQASMS VKFGFQKPLR DDAFLESRPL SKCKVSSEET IPFLYELKGL
     701  LGNDS*

external links for Inp2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Inp2p

1)	Fagarasanu A, et al. (2006) The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae. Dev Cell 10(5):587-600
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41