YIM1/YMR152W Protein Information

Standard Name	Yim1p
Systematic Name	Ymr152wp
ORF Classification	Verified
Description	Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress (1, 2, 3)

Experimental Data
Molecules/cell	6540 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	365
Molecular Weight (Da)	41,637
Isoelectric Point (pI)	7.98

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yim1p (InterPro)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B8D0 \| P28625 MIPS: YMR152W NCBI: 234847 \| 45270728 \| 606451 \| 6323801 \| 732169 \| 825557 \| NP_013872.1 \| NM_001182654.1 GenBank/EMBL/DDBJ: DAA10047.1 \| AY558419 \| S55518 \| Z47071 \| Z49705

Amino Acid Sequence (or in FASTA format)
1 MSDEIVTNKS VTYVNNTTPV TITSSELDLR SCYQDDEVVI EVHAAALNPI 51 DFITHQLCNS YIFGKYPKTY SRDYSGVIIK AGKDVDNRWK VGDKVNGMYS 101 HIYGERGTLT HYLILNPAKD VPITHMVEVP KDENDPYDDF VYAAAWPLTF 151 GTAFSTLYDF KKDWTSDSKV LVIGASTSVS YAFVHIAKNY FNIGTVVGIC 201 SKNSIERNKK LGYDYLVPYD EGSIVENVKK LKQSVLENDK FDMIFDSVGN 251 HDFFPVIDQF LKPKAKNSFY VTIAGNNKAD YKNISWRDFV SLSSILKAIN 301 PFKKYNWRFG HPYPPNNFIE VGNEMIKKGT YKPPIDSVYE FDQYKEAIDR 351 LMSNRAKGKV VVKMK*

Amino Acid Sequence (or in FASTA format)

       1  MSDEIVTNKS VTYVNNTTPV TITSSELDLR SCYQDDEVVI EVHAAALNPI
      51  DFITHQLCNS YIFGKYPKTY SRDYSGVIIK AGKDVDNRWK VGDKVNGMYS
     101  HIYGERGTLT HYLILNPAKD VPITHMVEVP KDENDPYDDF VYAAAWPLTF
     151  GTAFSTLYDF KKDWTSDSKV LVIGASTSVS YAFVHIAKNY FNIGTVVGIC
     201  SKNSIERNKK LGYDYLVPYD EGSIVENVKK LKQSVLENDK FDMIFDSVGN
     251  HDFFPVIDQF LKPKAKNSFY VTIAGNNKAD YKNISWRDFV SLSSILKAIN
     301  PFKKYNWRFG HPYPPNNFIE VGNEMIKKGT YKPPIDSVYE FDQYKEAIDR
     351  LMSNRAKGKV VVKMK*

external links for Yim1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Yim1p

1)	Birrell GW, et al. (2002) Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci U S A 99(13):8778-83
2)	Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
3)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41