YMR102C Protein Information Help

Systematic Name Ymr102cp
ORF Classification Uncharacterized
Description Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; not an essential gene; YMR102C has a paralog, DGR2, that arose from the whole genome duplication (1, 2, 3, 4)
Experimental Data
Molecules/cell 538 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 834
Molecular Weight (Da) 94,254
Isoelectric Point (pI) 9

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ymr102cp (InterPro)
Physical Interactions There are 14 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013BA4C | Q03177
MIPS: YMR102C
NCBI: 2494912 | 6323749 | 817860 | 854439 | 927539 | NP_013820.1
GenBank/EMBL/DDBJ: DAA09999.1 | Z49702 | Z49807 | Z50179
Amino Acid Sequence (or in FASTA format)
 
       1  MTNMAEDKTS ISKVHSEFSN SSNTTGSEEE SRSHQESFDG ESSSGESKSK
      51  SKLNLEYSAD IEPLKFRMTK TNNTNDKLKY SNNGNATDSF MRLKEHLQRG
     101  NTLNSNLRVN EFYPFNSIDT EQFENYLREP KYIKMLKRRK NLKQFRRLFL
     151  AQELMAYEGE TVTSTSKSSE PTSKAIWSTK FSRDGKFMAT GSKDGKIRIW
     201  KVIGSPVERA ELDSSAESNK EARAKSMRIK QQVSSLNNPK EKQFLDSATE
     251  KYEEKEKLLN LYAPVFHPTP LRLYKEHVQD VLDINWSKNN FILSASMDKT
     301  VKLWHPDRKN SLKTFIHPDF VTCVEFHPTD DRFFISGCLD HKCRLWSILD
     351  DEVSFEYDCQ DLITSVTLSP EEGKYTIIGT FNGYVHILMT RGLTPVSSFH
     401  VADRQTQEQN AHVMVTETDS KIRHGPRVTG LQAFRSQLDN SFRLVVTSND
     451  SRIRIFDLEQ RKLLEVLKGF HSGSSQHKAQ LSIWHGQPIV VNSSDDHWVY
     501  GWRLKSSDRE NDQDEPKRKP KGLARSGSLR SIFSKSMSRS SSQNNEEKPH
     551  HHLKLTNLLP LPHHSNDHYI KNTDYISFHA HNAPVTCVSI APPETSKTLS
     601  LSNDVICELS LEFFQTSDSF DVLSRSNDDG IMSDVESSLG YNSKPGSISN
     651  ASATSAIPDV VDAIGTILIS TDNVGTIRVF RADMPSVIRK RVLLKLEEYN
     701  REVRRRFNSS DSLHSLSRSF NSRAKSNLAG QPAAAYTNTG KGYATGRGYS
     751  NICPKSSTSL KTLGSNAQPR TPRESMSSIF SNAHGPTTPT SAMNLPIRCN
     801  VCNGSRFEAF SGANDQQDRN YYCVDCGTVV NNFR*

external links for Ymr102cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Ymr102cp
1) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2) Anderson JB, et al.  (2003) Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics 163(4):1287-98
3) Lucau-Danila A, et al.  (2003) Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J Biol Chem 278(52):52641-50
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41