ADH3/YMR083W Protein Information

Standard Name	Adh3p 1
Systematic Name	Ymr083wp
ORF Classification	Verified
Description	Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production (2, 3)
Name Description	Alcohol DeHydrogenase

Experimental Data
Molecules/cell	11600 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	375
Molecular Weight (Da)	40,369
Isoelectric Point (pI)	8.52

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Adh3p (InterPro)
Physical Interactions	There are 23 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000125584 \| P07246 MIPS: YMR083W NCBI: 1351880 \| 171023 \| 51013427 \| 6323729 \| 807965 \| NP_013800.1 GenBank/EMBL/DDBJ: DAA09980.1 \| AY692988 \| K03292 \| Z49259
External Classifications	EC: 1.1.1.1 [Alcohol dehydrogenase] EC: 1.1.1.190 [Indole-3-acetaldehyde reductase (NADH)]

Amino Acid Sequence (or in FASTA format)
1 MLRTSTLFTR RVQPSLFSRN ILRLQSTAAI PKTQKGVIFY ENKGKLHYKD 51 IPVPEPKPNE ILINVKYSGV CHTDLHAWHG DWPLPVKLPL VGGHEGAGVV 101 VKLGSNVKGW KVGDLAGIKW LNGSCMTCEF CESGHESNCP DADLSGYTHD 151 GSFQQFATAD AIQAAKIQQG TDLAEVAPIL CAGVTVYKAL KEADLKAGDW 201 VAISGAAGGL GSLAVQYATA MGYRVLGIDA GEEKEKLFKK LGGEVFIDFT 251 KTKNMVSDIQ EATKGGPHGV INVSVSEAAI SLSTEYVRPC GTVVLVGLPA 301 NAYVKSEVFS HVVKSINIKG SYVGNRADTR EALDFFSRGL IKSPIKIVGL 351 SELPKVYDLM EKGKILGRYV VDTSK*

Amino Acid Sequence (or in FASTA format)

       1  MLRTSTLFTR RVQPSLFSRN ILRLQSTAAI PKTQKGVIFY ENKGKLHYKD
      51  IPVPEPKPNE ILINVKYSGV CHTDLHAWHG DWPLPVKLPL VGGHEGAGVV
     101  VKLGSNVKGW KVGDLAGIKW LNGSCMTCEF CESGHESNCP DADLSGYTHD
     151  GSFQQFATAD AIQAAKIQQG TDLAEVAPIL CAGVTVYKAL KEADLKAGDW
     201  VAISGAAGGL GSLAVQYATA MGYRVLGIDA GEEKEKLFKK LGGEVFIDFT
     251  KTKNMVSDIQ EATKGGPHGV INVSVSEAAI SLSTEYVRPC GTVVLVGLPA
     301  NAYVKSEVFS HVVKSINIKG SYVGNRADTR EALDFFSRGL IKSPIKIVGL
     351  SELPKVYDLM EKGKILGRYV VDTSK*

external links for Adh3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Adh3p

1)	Ciriacy, M. (1985) Personal Communication, Mortimer Map Edition 9
2)	Bakker BM, et al. (2000) The mitochondrial alcohol dehydrogenase Adh3p is involved in a redox shuttle in Saccharomyces cerevisiae. J Bacteriol 182(17):4730-7
3)	Bakker BM, et al. (2001) Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae. FEMS Microbiol Rev 25(1):15-37
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41