STV1/YMR054W Protein Information Help

Standard Name Stv1p
Systematic Name Ymr054wp
ORF Classification Verified
Description Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole (1, 2, 3, 4)
Name Description Similar To VPH1 1
Experimental Data
Molecules/cell 1080 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 890
Molecular Weight (Da) 101,660
Isoelectric Point (pI) 5.13

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Stv1p (InterPro)
Transmembrane Domains There are 7 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 47 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013615B | P37296
MIPS: YMR054W
NCBI: 1711568 | 460160 | 6323699 | 817887 | NP_013770.1
GenBank/EMBL/DDBJ: DAA09953.1 | U06465 | Z49703
External Classifications EC: 3.6.3.14 [H(+)-transporting two-sector ATPase]
Amino Acid Sequence (or in FASTA format)
 
       1  MNQEEAIFRS ADMTYVQLYI PLEVIREVTF LLGKMSVFMV MDLNKDLTAF
      51  QRGYVNQLRR FDEVERMVGF LNEVVEKHAA ETWKYILHID DEGNDIAQPD
     101  MADLINTMEP LSLENVNDMV KEITDCESRA RQLDESLDSL RSKLNDLLEQ
     151  RQVIFECSKF IEVNPGIAGR ATNPEIEQEE RDVDEFRMTP DDISETLSDA
     201  FSFDDETPQD RGALGNDLTR NQSVEDLSFL EQGYQHRYMI TGSIRRTKVD
     251  ILNRILWRLL RGNLIFQNFP IEEPLLEGKE KVEKDCFIIF THGETLLKKV
     301  KRVIDSLNGK IVSLNTRSSE LVDTLNRQID DLQRILDTTE QTLHTELLVI
     351  HDQLPVWSAM TKREKYVYTT LNKFQQESQG LIAEGWVPST ELIHLQDSLK
     401  DYIETLGSEY STVFNVILTN KLPPTYHRTN KFTQAFQSIV DAYGIATYKE
     451  INAGLATVVT FPFMFAIMFG DMGHGFILFL MALFLVLNER KFGAMHRDEI
     501  FDMAFTGRYV LLLMGAFSVY TGLLYNDIFS KSMTIFKSGW QWPSTFRKGE
     551  SIEAKKTGVY PFGLDFAWHG TDNGLLFSNS YKMKLSILMG YAHMTYSFMF
     601  SYINYRAKNS KVDIIGNFIP GLVFMQSIFG YLSWAIVYKW SKDWIKDDKP
     651  APGLLNMLIN MFLAPGTIDD QLYSGQAKLQ VVLLLAALVC VPWLLLYKPL
     701  TLRRLNKNGG GGRPHGYQSV GNIEHEEQIA QQRHSAEGFQ GMIISDVASV
     751  ADSINESVGG GEQGPFNFGD VMIHQVIHTI EFCLNCISHT ASYLRLWALS
     801  LAHAQLSSVL WDMTISNAFS SKNSGSPLAV MKVVFLFAMW FVLTVCILVF
     851  MEGTSAMLHA LRLHWVEAMS KFFEGEGYAY EPFSFRAIIE *

external links for Stv1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Stv1p
1) Manolson MF, et al.  (1994) STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1p. J Biol Chem 269(19):14064-74
2) Manolson MF, et al.  (1992) The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. J Biol Chem 267(20):14294-303
3) Graham LA and Stevens TH  (1999) Assembly of the yeast vacuolar proton-translocating ATPase. J Bioenerg Biomembr 31(1):39-47
4) Kawasaki-Nishi S, et al.  (2001) Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation. J Biol Chem 276(21):17941-8
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41