FAR8/YMR029C Protein Information

Standard Name	Far8p 1
Systematic Name	Ymr029cp
ORF Classification	Verified
Description	Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p (1)
Name Description	Factor ARrest 2

Experimental Data
Molecules/cell	4010 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	523
Molecular Weight (Da)	59,301
Isoelectric Point (pI)	4.97

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Far8p (InterPro)
Physical Interactions	There are 18 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BA14 \| Q05040 MIPS: YMR029C NCBI: 2497122 \| 6323671 \| 798954 \| NP_013742.1 GenBank/EMBL/DDBJ: DAA09927.1 \| Z49213

Amino Acid Sequence (or in FASTA format)
1 MAINQAHVHP HYTLPGVMHY LQTEFTKNER DRITWELERS EMKARIAELE 51 GENRDLKHQL NQIQSKAVSP EGEKEEKHVP DSLLQSKLAV QENVKEIIYL 101 LKGPNTVNQL ESLNSREAGS ELHDLEKLNV NTPKEEGSAK TNGMDILNNA 151 LLDTKPNPKQ GPSESPSPTK VKSLFSTANK RENNETISKI HSELSKVDII 201 SSYGDCMALY DADTKSLEIH QVDANLNSKL LKKISLGQDS DIMKFFWVST 251 SKLLVIEKSF HLKLFSISSA SLISDVDLLQ DSEQPFSSSD IINIDFKNKW 301 LLIASKNKSQ IRIWELDNIE APEDVPINIK ETYEITHDND DDDSNDSTNI 351 LDCILGITEK SLILLSSNPY QLTIYDFEGK LLQKIDLKID TILSGKPEEE 401 GYHLFLDRKT SKLLIQLSNE RLLVYSFDKK KVVLKEQLTP SSTLPIQLDL 451 NDSIITVSYS NGDFEFRNLE NLKPSIDEFV VADINFSERK EPVVFSSNLI 501 VDSTPVLITV NKNNEVLLHK IKI*

Amino Acid Sequence (or in FASTA format)

       1  MAINQAHVHP HYTLPGVMHY LQTEFTKNER DRITWELERS EMKARIAELE
      51  GENRDLKHQL NQIQSKAVSP EGEKEEKHVP DSLLQSKLAV QENVKEIIYL
     101  LKGPNTVNQL ESLNSREAGS ELHDLEKLNV NTPKEEGSAK TNGMDILNNA
     151  LLDTKPNPKQ GPSESPSPTK VKSLFSTANK RENNETISKI HSELSKVDII
     201  SSYGDCMALY DADTKSLEIH QVDANLNSKL LKKISLGQDS DIMKFFWVST
     251  SKLLVIEKSF HLKLFSISSA SLISDVDLLQ DSEQPFSSSD IINIDFKNKW
     301  LLIASKNKSQ IRIWELDNIE APEDVPINIK ETYEITHDND DDDSNDSTNI
     351  LDCILGITEK SLILLSSNPY QLTIYDFEGK LLQKIDLKID TILSGKPEEE
     401  GYHLFLDRKT SKLLIQLSNE RLLVYSFDKK KVVLKEQLTP SSTLPIQLDL
     451  NDSIITVSYS NGDFEFRNLE NLKPSIDEFV VADINFSERK EPVVFSSNLI
     501  VDSTPVLITV NKNNEVLLHK IKI*

external links for Far8p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Far8p

1)	Kemp HA and Sprague Jr GF Jr (2003) Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae. Mol Cell Biol 23(5):1750-63
2)	Chang F and Herskowitz I (1990) Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell 63(5):999-1011
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41