STB4/YMR019W Protein Information Help

Standard Name Stb4p
Systematic Name Ymr019wp
ORF Classification Verified
Description Putative transcription factor; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters; binds Sin3p in a two-hybrid assay; (1, 2, 3)
Name Description Sin Three Binding protein
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 949
Molecular Weight (Da) 109,824
Isoelectric Point (pI) 7.28

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Stb4p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 12 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001360AE | P50104
MIPS: YMR019W
NCBI: 1730632 | 6323661 | 798929 | NP_013732.1
GenBank/EMBL/DDBJ: DAA09917.1 | Z49211
Amino Acid Sequence (or in FASTA format)
 
       1  MSINHEIYYI LVFEHRSVAI KLIIVVIVLL QFFLARSRQI DRTWAHTNRK
      51  ERFREMTAIG NTDDALDTST AASKENGKGR LRVQKACELC KKRKVKCDGN
     101  NPCLNCSKHQ KECRYDFKAT NRKRRRRQVA SAVRDVSKTY AETSESFPRD
     151  LLSKSNIIIN APSDGVSSSA SNSPNPNSHY HHISSTLPFM SGRPNHTFHS
     201  GSNLNGENNN NSFPEDHMAK LLLQLSSKLG NTTKESSIRT TRTNASDVNA
     251  NPTVVNMKNS QEDCDTNHRS AICDSAEALH NNNINSKENK IINSQITNTV
     301  NDHFESPWQT FSLDKYRFHR RYQNILPYYL GVSILKDLSP QTIEYAKLKR
     351  PRVQNYGWNL SGGHYLKYKG DFRSQEKNIR HESKFFDFDD PVHLSLINKL
     401  LRYYFDEINP VFSIIHEATF WQQYNNKFLR QGKQNNSSAN LFTSMLYLIL
     451  STTLRFREGH LDGQKGQGTY SNTSLNITFE EKSILIKKPS IEENLFKYAY
     501  LIINTLTFEW ESFELIQSWL LITFYFRTCY RQTACWNALS QAVNMCNGMS
     551  LYLNKFPEIH STYDESKAWH CFWCCFIMDK LISFQMGRFY QLSLPASEMC
     601  EQMNLVKSKK FLQEEDDWFH EETFQMLDLS IIVTQFLKRD AQDLNLNETV
     651  QLRSQLGQWY DTFIVGSQTN AYDDNYRYFY QVQPFMTYLD IRLTFEVRQL
     701  FCLIAPSSTA NNKSLEYVVD TELLISHCQM AIENLAEITR SNLFFVPWWL
     751  NLSQLFTVNL ICIIYLHAGI AVTQNKAIMQ SCQEIWRTLE CSKPKNRPSM
     801  LPECLWCLKM LNHMFCIRLR DSALQLEATL GTDHGDDTPN RNKFEQFKKV
     851  GDNDADVEVD AGEREENADE RQENPHNNSK RVPLATRSHN TTNFDGSIAI
     901  SPESAVANLG TDTGLPSDVL DTVSKIGNSP NVFDDDLFSN LLWFDQNFA*

external links for Stb4p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Stb4p
1) Kasten MM and Stillman DJ  (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256(4):376-86
2) Ward LD and Bussemaker HJ  (2008) Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences. Bioinformatics 24(13):i165-71
3) Yang Y, et al.  (2010) Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Cell Res 20(11):1276-8