HXT2/YMR011W Protein Information

Standard Name	Hxt2p
Systematic Name	Ymr011wp
ORF Classification	Verified
Description	High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose (1, 2)
Name Description	HeXose Transporter

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	541
Molecular Weight (Da)	59,840
Isoelectric Point (pI)	8.31

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Hxt2p (InterPro)
Transmembrane Domains	There are 12 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 14 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000004F954 \| P23585 MIPS: YMR011W NCBI: 123903 \| 171743 \| 6323653 \| 728660 \| NP_013724.1 GenBank/EMBL/DDBJ: DAA09909.1 \| M33270 \| Z48613
External Classifications	TC: 2.A.1.1 [The Sugar Porter (SP) Family]

Amino Acid Sequence (or in FASTA format)
1 MSEFATSRVE SGSQQTSIHS TPIVQKLETD ESPIQTKSEY TNAELPAKPI 51 AAYWTVICLC LMIAFGGFVF GWDTGTISGF VNQTDFKRRF GQMKSDGTYY 101 LSDVRTGLIV GIFNIGCAFG GLTLGRLGDM YGRRIGLMCV VLVYIVGIVI 151 QIASSDKWYQ YFIGRIISGM GVGGIAVLSP TLISETAPKH IRGTCVSFYQ 201 LMITLGIFLG YCTNYGTKDY SNSVQWRVPL GLNFAFAIFM IAGMLMVPES 251 PRFLVEKGRY EDAKRSLAKS NKVTIEDPSI VAEMDTIMAN VETERLAGNA 301 SWGELFSNKG AILPRVIMGI MIQSLQQLTG NNYFFYYGTT IFNAVGMKDS 351 FQTSIVLGIV NFASTFVALY TVDKFGRRKC LLGGSASMAI CFVIFSTVGV 401 TSLYPNGKDQ PSSKAAGNVM IVFTCLFIFF FAISWAPIAY VIVAESYPLR 451 VKNRAMAIAV GANWIWGFLI GFFTPFITSA IGFSYGYVFM GCLVFSFFYV 501 FFFVCETKGL TLEEVNEMYV EGVKPWKSGS WISKEKRVSE E*

Amino Acid Sequence (or in FASTA format)

       1  MSEFATSRVE SGSQQTSIHS TPIVQKLETD ESPIQTKSEY TNAELPAKPI
      51  AAYWTVICLC LMIAFGGFVF GWDTGTISGF VNQTDFKRRF GQMKSDGTYY
     101  LSDVRTGLIV GIFNIGCAFG GLTLGRLGDM YGRRIGLMCV VLVYIVGIVI
     151  QIASSDKWYQ YFIGRIISGM GVGGIAVLSP TLISETAPKH IRGTCVSFYQ
     201  LMITLGIFLG YCTNYGTKDY SNSVQWRVPL GLNFAFAIFM IAGMLMVPES
     251  PRFLVEKGRY EDAKRSLAKS NKVTIEDPSI VAEMDTIMAN VETERLAGNA
     301  SWGELFSNKG AILPRVIMGI MIQSLQQLTG NNYFFYYGTT IFNAVGMKDS
     351  FQTSIVLGIV NFASTFVALY TVDKFGRRKC LLGGSASMAI CFVIFSTVGV
     401  TSLYPNGKDQ PSSKAAGNVM IVFTCLFIFF FAISWAPIAY VIVAESYPLR
     451  VKNRAMAIAV GANWIWGFLI GFFTPFITSA IGFSYGYVFM GCLVFSFFYV
     501  FFFVCETKGL TLEEVNEMYV EGVKPWKSGS WISKEKRVSE E*

external links for Hxt2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	TCDB
	DIP	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Hxt2p

1)	Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2)	Ozcan S and Johnston M (1995) Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol Cell Biol 15(3):1564-72