YML133C Protein Information Help

Systematic Name Yml133cp
ORF Classification Uncharacterized
Description Putative Y' element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron (1, 2, 3)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,374
Molecular Weight (Da) 155,552
Isoelectric Point (pI) 7.98

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Yml133cp (InterPro)
Physical Interactions There are 3 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B9FB | Q03099
MIPS: YML133C
NCBI: 1326004 | 2497057 | 6323502 | 927529 | NP_013573.1 | NM_001182496.1
GenBank/EMBL/DDBJ: DAA09766.1 | Z50178
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
EC: 3.6.4.12 [DNA helicase]
Amino Acid Sequence (or in FASTA format)
 
       1  MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE
      51  KSGLIKVVKF RTGAMDRKRS FEKIVVSVMV GKNVQKFLTF VEDEPDFQGG
     101  PIPSKYLIPK KINLMVYTLF QVHTLKFNRK DYDTLSLFYL NRGYYNELSF
     151  RVLERCHEIA SARPNDSSTM RTFTDFVSGA PIVRSLQKST IRRYGYNLAP
     201  HMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK PIEIKYFSQI
     251  CNDMMNKKDR LGDVLATAQR IRRRYNKNSS SEPRLKTLDG LTSERWIQWL
     301  GLESDYHCSF SSTRNAEDVV AGEAASSDHH QKISRVTRKR PREPKSTNDI
     351  LVAGQKLFGS SFEFRDLHQL RLCHEIYMAD TPSVAVQAPP GYGKTELFHL
     401  PLIALASKGD VKYVSFLFVP YTVLLANCMI RLSRCGCLNV APVRNFIEEG
     451  CDGVTDLYVG IYDDLASTNF TDRIAAWENI VECTFRTNNV KLGYLIVDEF
     501  HNFETEVYRQ SQFGGITNLD FDAFEKAIFL SGTAPEAVAD AALQRIGLTG
     551  LAKKSMDINE LKRSEDLSRG LSSYPTRMFN LIKEKSEVPL GHVHKIWKKV
     601  ESQPEEALKL LLALFEIEPE SKAIVVASTT NEVEELACSW RKYFRVVWIH
     651  GKLGAAEKVS RTKEFVTDGS MRVLIGTKLV TEGIDIKQLM MVIMLDNRLN
     701  IIELIQGVGR LRDGGLCYLL SRKNSWAARN RKGELPPIKE GCITEQVREF
     751  YGLESKKGKK GQHVGCCGSR TDLSADTVEL IERMDRLAEK QATASMSIVA
     801  LPSSFQESNS SDRCRKYCSS DEDSDTCIHG SANASTNATT NSSTNATTTA
     851  STNVRTSATT TASINVRTSA TTTESTNSST NATTTASTNV RTSATTTASI
     901  NVRTSATTTE STNSNTSATT TESTDSNTSA TTTESTDSNT SATTTASTNS
     951  STNATTTAST NSSTNATTTE STNASAKEDA NKDGNAEDNR FHPVTDINKE
    1001  SYKRKGSQMV LLERKKLKAQ FPNTSENMNV LQFLGFRSDE IKHLFLYGID
    1051  IYFCPEGVFT QYGLCKGCQK MFELCVCWAG QKVSYRRMAW EALAVERMLR
    1101  NDEEYKEYLE DIEPYHGDPV GYLKFFSVKR GEIYSQIQRN YAWYLAITRR
    1151  RETISVLDST RGKQGSQVFR MSGRQIKELY YKVWSNLRES KTEVLQYFLN
    1201  WDEKKCREEW EAKDDTVFVE ALEKVGVFQR LRSMTSAGLQ GPQYVKLQFS
    1251  RHHRQLRSRY ELSLGMHLRD QLALGVTPSK VPHWTAFLSM LIGLFYNKTF
    1301  RQKLEYLLEQ ISEVWLLPHW VDLANVEVLA ADNTRVPLYM LMVAVHKELD
    1351  SDDVPDGRFD IILLCRDSSR EVGE*

external links for Yml133cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Yml133cp
1) Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6
2) Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
3) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54