UFO1/YML088W Protein Information Help

Standard Name Ufo1p 1
Systematic Name Yml088wp
ORF Classification Verified
Description F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation (1)
Name Description UV-F-box-HO 1
Experimental Data
Molecules/cell 639 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 668
Molecular Weight (Da) 76,859
Isoelectric Point (pI) 5.1

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ufo1p (InterPro)
Physical Interactions There are 55 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B9D5 | Q04511
MIPS: YML088W
NCBI: 2497075 | 575715 | 6323551 | NP_013622.1
GenBank/EMBL/DDBJ: DAA09809.1 | Z46660
Amino Acid Sequence (or in FASTA format)
 
       1  MERPGLVLQD LPPEILINIF SHLDEKDLFT LQELSTHFRN LIHDEELWKN
      51  LFKSRVHTTH FPTFSQSSKF SVEYIERTRG LHHWQHNKAI RTKYTIIPTR
     101  NWDQPSIERI VFDYPRVAAY NDGTITILQL QNHKRQKKFK KLIYIPCTTP
     151  QGCSTMDFNI NAAVFGRFDG RVFGKLLSNK SYLTPVMEFT GRHSAGVTAI
     201  CNSESWDTSR EDWSVSGSEN GEIIWWCENK LVKMWKVSNR VIWKLAFFKD
     251  WTLIMDDEKL YIIHQMQELH SIDIPKDLDE QPMRVRFFKM DFGSMTLVLA
     301  DLNNVYTISV NPNGNFGNLR KLEMPEQICA VEIDEKTSQR EQNWQFAGDD
     351  GCYISLLTTQ NTLYIINIRD LSSSGLKVQC KISFDEQVYV SQVTNLIVVV
     401  ALPNVLQILN AMTGELIKTV LKTEKFPEFL KVSQDKIIMG SGNVLNYLKF
     451  VSSDSKKHHH STKGKNTVSN KWNETLNTEL QYYDEDEDLR RKRQSEISRL
     501  IDAYGGDLEL SGDTDEENDI QLRIALLESQ EAQARNQAEA GEPVGDDEDE
     551  QLRRALEESQ LIYETQTNSS ANHGNNTNDE IDEDDEEFLR AIRQSRVEDE
     601  RRRHLRNHTT GRRNGPLSDD NFATYGAAES SERTSTENTI GSSVGVDASN
     651  NVDEDLQLAI ALSLSEIN*

external links for Ufo1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
YGOB CYC2008 (complexes) Pfam domains
YOGY Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ufo1p
1) Kaplun L, et al.  (2003) DNA damage response-mediated degradation of Ho endonuclease via the ubiquitin system involves its nuclear export. J Biol Chem 278(49):48727-34
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41