DAK1/YML070W Protein Information

Standard Name	Dak1p 1
Systematic Name	Yml070wp
ORF Classification	Verified
Description	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation (2)
Name Description	DihydroxyAcetone Kinase 1

Experimental Data
Molecules/cell	23600 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	584
Molecular Weight (Da)	62,206
Isoelectric Point (pI)	5.14

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Dak1p (InterPro)
Physical Interactions	There are 11 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000128E18 \| P54838 MIPS: YML070W NCBI: 1706391 \| 558404 \| 6323570 \| NP_013641.1 GenBank/EMBL/DDBJ: DAA09827.1 \| Z38114
External Classifications	EC: 2.7.1.28 [Triokinase] EC: 2.7.1.29 [Glycerone kinase]

Amino Acid Sequence (or in FASTA format)
1 MSAKSFEVTD PVNSSLKGFA LANPSITLVP EEKILFRKTD SDKIALISGG 51 GSGHEPTHAG FIGKGMLSGA VVGEIFASPS TKQILNAIRL VNENASGVLL 101 IVKNYTGDVL HFGLSAERAR ALGINCRVAV IGDDVAVGRE KGGMVGRRAL 151 AGTVLVHKIV GAFAEEYSSK YGLDGTAKVA KIINDNLVTI GSSLDHCKVP 201 GRKFESELNE KQMELGMGIH NEPGVKVLDP IPSTEDLISK YMLPKLLDPN 251 DKDRAFVKFD EDDEVVLLVN NLGGVSNFVI SSITSKTTDF LKENYNITPV 301 QTIAGTLMTS FNGNGFSITL LNATKATKAL QSDFEEIKSV LDLLNAFTNA 351 PGWPIADFEK TSAPSVNDDL LHNEVTAKAV GTYDFDKFAE WMKSGAEQVI 401 KSEPHITELD NQVGDGDCGY TLVAGVKGIT ENLDKLSKDS LSQAVAQISD 451 FIEGSMGGTS GGLYSILLSG FSHGLIQVCK SKDEPVTKEI VAKSLGIALD 501 TLYKYTKARK GSSTMIDALE PFVKEFTASK DFNKAVKAAE EGAKSTATFE 551 AKFGRASYVG DSSQVEDPGA VGLCEFLKGV QSAL*

Amino Acid Sequence (or in FASTA format)

       1  MSAKSFEVTD PVNSSLKGFA LANPSITLVP EEKILFRKTD SDKIALISGG
      51  GSGHEPTHAG FIGKGMLSGA VVGEIFASPS TKQILNAIRL VNENASGVLL
     101  IVKNYTGDVL HFGLSAERAR ALGINCRVAV IGDDVAVGRE KGGMVGRRAL
     151  AGTVLVHKIV GAFAEEYSSK YGLDGTAKVA KIINDNLVTI GSSLDHCKVP
     201  GRKFESELNE KQMELGMGIH NEPGVKVLDP IPSTEDLISK YMLPKLLDPN
     251  DKDRAFVKFD EDDEVVLLVN NLGGVSNFVI SSITSKTTDF LKENYNITPV
     301  QTIAGTLMTS FNGNGFSITL LNATKATKAL QSDFEEIKSV LDLLNAFTNA
     351  PGWPIADFEK TSAPSVNDDL LHNEVTAKAV GTYDFDKFAE WMKSGAEQVI
     401  KSEPHITELD NQVGDGDCGY TLVAGVKGIT ENLDKLSKDS LSQAVAQISD
     451  FIEGSMGGTS GGLYSILLSG FSHGLIQVCK SKDEPVTKEI VAKSLGIALD
     501  TLYKYTKARK GSSTMIDALE PFVKEFTASK DFNKAVKAAE EGAKSTATFE
     551  AKFGRASYVG DSSQVEDPGA VGLCEFLKGV QSAL*

external links for Dak1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Dak1p

1)	Norbeck J and Blomberg A (1997) Metabolic and regulatory changes associated with growth of Saccharomyces cerevisiae in 1.4 M NaCl. Evidence for osmotic induction of glycerol dissimilation via the dihydroxyacetone pathway. J Biol Chem 272(9):5544-54
2)	Molin M, et al. (2003) Dihydroxyacetone kinases in Saccharomyces cerevisiae are involved in detoxification of dihydroxyacetone. J Biol Chem 278(3):1415-23
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41