OST6/YML019W Protein Information

Standard Name	Ost6p 1
Systematic Name	Yml019wp
ORF Classification	Verified
Description	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p (1, 2)
Name Description	OligoSaccharylTransferase 1

Experimental Data
Molecules/cell	1080 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	332
Molecular Weight (Da)	37,890
Isoelectric Point (pI)	8.53

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ost6p (InterPro)
Transmembrane Domains	There are 4 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 41 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000005303C \| Q03723 MIPS: YML019W NCBI: 240104443 \| 240104444 \| 240104449 \| 2463436 \| 2497104 \| 51013399 \| 575700 \| 6323622 \| NP_013693.1 GenBank/EMBL/DDBJ: DAA09879.1 \| AY692974 \| Y08606 \| Z46659

Amino Acid Sequence (or in FASTA format)
1 MKWCSTYIII WLAIIFHKFQ KSTATASHNI DDILQLKDDT GVITVTADNY 51 PLLSRGVPGY FNILYITMRG TNSNGMSCQL CHDFEKTYHA VADVIRSQAP 101 QSLNLFFTVD VNEVPQLVKD LKLQNVPHLV VYPPAESNKQ SQFEWKTSPF 151 YQYSLVPENA ENTLQFGDFL AKILNISITV PQAFNVQEFV YYFVACMVVF 201 IFIKKVILPK VTNKWKLFSM ILSLGILLPS ITGYKFVEMN AIPFIARDAK 251 NRIMYFSGGS GWQFGIEIFS VSLMYIVMSA LSVLLIYVPK ISCVSEKMRG 301 LLSSFLACVL FYFFSYFISC YLIKNPGYPI VF*

Amino Acid Sequence (or in FASTA format)

       1  MKWCSTYIII WLAIIFHKFQ KSTATASHNI DDILQLKDDT GVITVTADNY
      51  PLLSRGVPGY FNILYITMRG TNSNGMSCQL CHDFEKTYHA VADVIRSQAP
     101  QSLNLFFTVD VNEVPQLVKD LKLQNVPHLV VYPPAESNKQ SQFEWKTSPF
     151  YQYSLVPENA ENTLQFGDFL AKILNISITV PQAFNVQEFV YYFVACMVVF
     201  IFIKKVILPK VTNKWKLFSM ILSLGILLPS ITGYKFVEMN AIPFIARDAK
     251  NRIMYFSGGS GWQFGIEIFS VSLMYIVMSA LSVLLIYVPK ISCVSEKMRG
     301  LLSSFLACVL FYFFSYFISC YLIKNPGYPI VF*

external links for Ost6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ost6p

1)	Knauer R and Lehle L (1999) The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex. J Biol Chem 274(24):17249-56
2)	Knauer R and Lehle L (1999) The oligosaccharyltransferase complex from yeast. Biochim Biophys Acta 1426(2):259-73
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41