YLR460C Protein Information

Systematic Name	Ylr460cp
ORF Classification	Uncharacterized
Description	Member of the quinone oxidoreductase family, up-regulated in response to the fungicide mancozeb; possibly up-regulated by iodine (1, 2, 3)

Experimental Data
Molecules/cell	799 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	376
Molecular Weight (Da)	41,127
Isoelectric Point (pI)	7.21

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ylr460cp (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B7D9 \| P54007 MIPS: YLR460C NCBI: 1730591 \| 398366381 \| 717077 \| NP_013565.3 GenBank/EMBL/DDBJ: DAA09759.1 \| U22383

Amino Acid Sequence (or in FASTA format)
1 MQVAIPETMK AVVIEDGKAV VKEGIPIPEL EEGFVLIKTL AVAGNPTDWA 51 HIDYKIGPQG SILGCDAAGQ IVKLGPAVNP KDFSIGDYIY GFIHGSSVRF 101 PSNGAFAEYS AISTVVAYKS PNELKFLGED VLPAGPVRSL EGVATIPVSL 151 TTAGLVLTYN LGLDLKWEPS TPQRKGPILL WGGATAVGQS LIQLANKLNG 201 FTKIIVVASR KHEKLLKEYG ADELFDYHDI DVVEQIKHKY NNISYLVDCV 251 ANQDTLQQVY KCAADKQDAT IVELKNLTEE NVKKENRRQN VTIDIIRLYS 301 IGGHEVPFGN ITLPADSEAR KAAIKFIKFI NPKINDGQIR HIPVRVYKNG 351 LCDVPHILKD IKYGKNSGEK LVAVLN*

Amino Acid Sequence (or in FASTA format)

       1  MQVAIPETMK AVVIEDGKAV VKEGIPIPEL EEGFVLIKTL AVAGNPTDWA
      51  HIDYKIGPQG SILGCDAAGQ IVKLGPAVNP KDFSIGDYIY GFIHGSSVRF
     101  PSNGAFAEYS AISTVVAYKS PNELKFLGED VLPAGPVRSL EGVATIPVSL
     151  TTAGLVLTYN LGLDLKWEPS TPQRKGPILL WGGATAVGQS LIQLANKLNG
     201  FTKIIVVASR KHEKLLKEYG ADELFDYHDI DVVEQIKHKY NNISYLVDCV
     251  ANQDTLQQVY KCAADKQDAT IVELKNLTEE NVKKENRRQN VTIDIIRLYS
     301  IGGHEVPFGN ITLPADSEAR KAAIKFIKFI NPKINDGQIR HIPVRVYKNG
     351  LCDVPHILKD IKYGKNSGEK LVAVLN*

external links for Ylr460cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ylr460cp

1)	Kitagawa E, et al. (2005) Effects of Iodine on Global Gene Expression in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 69(12):2285-93
2)	Riveros-Rosas H, et al. (2003) Diversity, taxonomy and evolution of medium-chain dehydrogenase/reductase superfamily. Eur J Biochem 270(16):3309-34
3)	Santos PM, et al. (2009) Insights into yeast adaptive response to the agricultural fungicide mancozeb: a toxicoproteomics approach. Proteomics 9(3):657-70
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41