YLR446W Protein Information

Systematic Name	Ylr446wp
ORF Classification	Uncharacterized
Description	Putative hexokinase; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene (1, 2, 3, 4)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	433
Molecular Weight (Da)	48,969
Isoelectric Point (pI)	5.69

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ylr446wp (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006BF98 \| Q06204 MIPS: YLR446W NCBI: 51012729 \| 6323479 \| 717064 \| 74644950 \| NP_013551.1 GenBank/EMBL/DDBJ: DAA09746.1 \| AY692639 \| U22382
External Classifications	EC: 2.7.1.1 [Hexokinase]

Amino Acid Sequence (or in FASTA format)
1 MTIESTLARE LESLILPADS IVNVVDQFQE ELLSRLQTNT ISMLPQCLVP 51 DKRSRWNPED KILTIDFGGT RLKFAIISLP QIVIEYNDAF ELTYNIVDSN 101 FFNQIIYTIC TRLAANGYIK KKNESSEASK FFVSVTFSFP LNPEGEVVAM 151 GKGFVMTDTL QGSTVKQLIQ SSFHRIISEN IEEFFCTMNV CHVINDAIAV 201 SLTSKFICEN DSISLIIGTG TNACFEVPYG YLPPFKRDAL RETLPSSYNK 251 ETLNFKHVLI NSEIGFIGKN VIALQPFDIH GAISYEMPLE CVTSGKWLPL 301 SLKNILLQYN IIPKNFPVEF NGELVCQLAE DCTNAWFENE HYALICQIAR 351 LLIKRAAFYV AAIVQAIDII TGCKNYNFIH IGYVGSFLHN SNFYREQIKY 401 YSSIHIKLQF LNHSNLLGAA IATYLNKSDN QVQ*

Amino Acid Sequence (or in FASTA format)

       1  MTIESTLARE LESLILPADS IVNVVDQFQE ELLSRLQTNT ISMLPQCLVP
      51  DKRSRWNPED KILTIDFGGT RLKFAIISLP QIVIEYNDAF ELTYNIVDSN
     101  FFNQIIYTIC TRLAANGYIK KKNESSEASK FFVSVTFSFP LNPEGEVVAM
     151  GKGFVMTDTL QGSTVKQLIQ SSFHRIISEN IEEFFCTMNV CHVINDAIAV
     201  SLTSKFICEN DSISLIIGTG TNACFEVPYG YLPPFKRDAL RETLPSSYNK
     251  ETLNFKHVLI NSEIGFIGKN VIALQPFDIH GAISYEMPLE CVTSGKWLPL
     301  SLKNILLQYN IIPKNFPVEF NGELVCQLAE DCTNAWFENE HYALICQIAR
     351  LLIKRAAFYV AAIVQAIDII TGCKNYNFIH IGYVGSFLHN SNFYREQIKY
     401  YSSIHIKLQF LNHSNLLGAA IATYLNKSDN QVQ*

external links for Ylr446wp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ylr446wp

1)	Chu S, et al. (1998) The transcriptional program of sporulation in budding yeast. Science 282(5389):699-705
2)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3)	Travers KJ, et al. (2000) Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101(3):249-58
4)	Balakrishnan R, et al. (2005) Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Nucleic Acids Res 33 Database Issue:D374-7