YLR419W Protein Information Help

Systematic Name Ylr419wp
ORF Classification Uncharacterized
Description Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene (1, 2, 3, 4, 5, 6)
Experimental Data
Molecules/cell 195 7
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,435
Molecular Weight (Da) 163,043
Isoelectric Point (pI) 9.86

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ylr419wp (InterPro)
Physical Interactions There are 6 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006A2CD | Q06698
MIPS: YLR419W
NCBI: 398366185 | 632671 | 74644973 | NP_013523.3
GenBank/EMBL/DDBJ: DAA09721.1 | U20162
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
EC: 3.6.4.13 [RNA helicase]
Amino Acid Sequence (or in FASTA format)
 
       1  MAKKTKNNSK SSTPVNDVPT TAGKKKAKGK KGQEPEPEDD KRAKQQSNRA
      51  KVTSTASWTG KLPHTILHET CQKRKWNKVE YDMKKIGDKG FIAIAVLSFT
     101  DPKTKETLTA RMNDPTYDKA SGKGLVIPQE TPIEARHMAS TIALYRIAYN
     151  TNLHMMLPPN HRKTWYALDD FRKDNLKTDE KRINKLFDLD PFKTMVEDRK
     201  LKAQREKEQV AQNNQAQKEQ VARTILSSHG GISSSGKDRQ ERKVASHKNS
     251  HNPSLVRFPK KVWENSIFVD LDESSRQLIE TSLKEKIDWQ AKKISHKNET
     301  IAENREDLKA KLLTLQFRPK HVEEAMLYKD PLSFLLFNLP EDDLPPFFHK
     351  KKGDTKNKVE ITNLPLSTRM IVERLTEIGV SSDEALLALQ QNDMNENEAA
     401  GFLTREILPT LNSNTNEPVS ETESIECWNQ ELESLESIYE GCVMDAKEDS
     451  HYTLNLIEKL KIKLKVYRTK NYPASLPGIV VSTFDKNYKL PDYIKKQILT
     501  RLLHYLQEGN LIGDMLVYHI YEWLKENISK IIDNPGPLIP DSDSKGAINK
     551  RNISNGKRSI NNSSSRKFTK TTISEDTLSV LREEYTKRIK SSEYKSMQLV
     601  REQLPAWKKQ KVIIDIINKN EVVLITGETG SGKSTQVVQF ILDFLQKEKG
     651  DFGKTKIVCT QPRRISAIGL AERVSDERCV TCGEEVGYVI RGVNKTKAST
     701  RIKFMTTGVL VRLLQNARTM LENTIVVIDE VHERSIDTDL IVTLMKNLLH
     751  RVRGMKIVLM SATVNVDLFK KFFPGLATCH IEGRTFPITD YFLEDILSDL
     801  DFKIKREKAL SYDDDSVDER NNDDQYLKPR ADSKFFTSGQ INYDLLCQVV
     851  EYVHKRLKAA NDNGSIIVFL PGVGEINKCC NLLANKSNEA DFMVLPLHSA
     901  LTPEDQKRVF KKYHGKRKVV VSTNIAETSI TIDDCVATID TGRAKSMFYN
     951  PKDNTTKLIE SFISKAEVKQ RRGRAGRVRE GLSYKLFSKN LYENDMISMP
    1001  IPEIKRIPLE SLYLSVKAMG IKDVKAFLST ALDAPPLPAL QKAERILTTI
    1051  GLVDESDKSL TQLGQFISLM PVMDSKHGKL LIYGILFGCT DISVLLVSIL
    1101  GIGVLPFIGG FENREKIKKL LCKYESRGDL FAVLEIVRDY FKIKDSSIKR
    1151  KYLRDNLLSY NKINEIKSST AQYYSILKDV GFLPMDYKVG SISDLNRNER
    1201  NFDILRAILT GAFYPHIARV QLPDVKYLST SSGAVEKDPE AKMIKYWIRS
    1251  EEYQDKLEEY KTKISQETQK VDLEDLPLPA TRAFIHPSSV LFSTNSVNLE
    1301  DAKLLSEVDG PISRQSKIPT VVKYPFVLFT TSQVTNKLYL RDLTPTTTLS
    1351  LLLFGGAISY DIGGTIHSPG IVVDNWLPIR TWCKNGVLIK ELRTQLDEAI
    1401  RKKLESPDYA KKSQIDNSGA DKTLKIVEKI IASEQ*

external links for Ylr419wp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Ylr419wp
1) Shiratori A, et al.  (1999) Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis. Yeast 15(3):219-53
2) Colley A, et al.  (2000) Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3. Mol Cell Biol 20(19):7238-46
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
5) Takemura M  (2005) Evolutionary history of the retinoblastoma gene from archaea to eukarya. Biosystems 82(3):266-72
6) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
7) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41