CTR3/YLR411W Protein Information

Standard Name	Ctr3p
Systematic Name	Ylr411wp
ORF Classification	Verified
Description	High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae (1, 2)
Name Description	Copper TRansport 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	241
Molecular Weight (Da)	27,534
Isoelectric Point (pI)	7.65

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ctr3p (InterPro)
Transmembrane Domains	There are 3 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052E9A \| Q06686 MIPS: YLR411W NCBI: 1778380 \| 2498268 \| 398366163 \| 51013309 \| 632675 \| NP_013515.3 GenBank/EMBL/DDBJ: DAA09713.1 \| AY692929 \| U20162 \| U81482

Amino Acid Sequence (or in FASTA format)
1 MNMGGSSSTA AKKATCKISM LWNWYTIDTC FIARSWRNDT KGKFAGSCIG 51 CFALVVVAQW LTRFSRQFDV ELLKRQKIKH LASYSPEEYV VKCGEEDAKS 101 DIEELQGFYN EPSWKTTLIS LQKSFIYSFY VWGPRRLNEP EDDLLKKVLS 151 CCTLITPVDL YPTFLDHMIR VTIFVLQWGL SYIIMLLFMY YNGYIIISCL 201 IGAIVGRFIF CYEPLGSLGA NGSAQGTVSY DKESDDRKCC L*

Amino Acid Sequence (or in FASTA format)

       1  MNMGGSSSTA AKKATCKISM LWNWYTIDTC FIARSWRNDT KGKFAGSCIG
      51  CFALVVVAQW LTRFSRQFDV ELLKRQKIKH LASYSPEEYV VKCGEEDAKS
     101  DIEELQGFYN EPSWKTTLIS LQKSFIYSFY VWGPRRLNEP EDDLLKKVLS
     151  CCTLITPVDL YPTFLDHMIR VTIFVLQWGL SYIIMLLFMY YNGYIIISCL
     201  IGAIVGRFIF CYEPLGSLGA NGSAQGTVSY DKESDDRKCC L*

external links for Ctr3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ctr3p

1)	Knight SA, et al. (1996) A widespread transposable element masks expression of a yeast copper transport gene. Genes Dev 10(15):1917-29
2)	Pena MM, et al. (2000) Characterization of the Saccharomyces cerevisiae high affinity copper transporter Ctr3. J Biol Chem 275(43):33244-51