BDF1/YLR399C Protein Information Help

Standard Name Bdf1p 1
Systematic Name Ylr399cp
ORF Classification Verified
Description Protein involved in transcription initiation; functions at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p; BDF1 has a paralog, BDF2, that arose from the whole genome duplication (2, 3)
Name Description BromoDomain Factor 1, 2
Experimental Data
Molecules/cell 8100 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 686
Molecular Weight (Da) 76,977
Isoelectric Point (pI) 5.86

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Bdf1p (InterPro)
Physical Interactions There are 148 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E57 | P35817
MIPS: YLR399C
NCBI: 311664 | 410319 | 5921175 | 608567 | 625115 | 6323431 | NP_013503.1 | NM_001182287.1
GenBank/EMBL/DDBJ: AAA35048.1 | AAA89115.1 | AAB82357.1 | CAA79377.1 | DAA09700.1 | L13469 | U18116 | U19729 | Z18944
Amino Acid Sequence (or in FASTA format)
       1  MTDITPVQND VDVNGNNVND DVSSNLKRPI DQGDPSNGLA EEENPANNQL
      51  HLKKARLDGD ALTSSPAGLA ENGIEGATLA ANGENGYNAT GSGAEDEQQG
     101  LKKEEGGQGT KQEDLDENSK QELPMEVPKE PAPAPPPEPD MNNLPQNPIP
     151  KHQQKHALLA IKAVKRLKDA RPFLQPVDPV KLDIPFYFNY IKRPMDLSTI
     201  ERKLNVGAYE VPEQITEDFN LMVNNSIKFN GPNAGISQMA RNIQASFEKH
     251  MLNMPAKDAP PVIAKGRRSS AQEDAPIVIR RAQTHNGRPK RTIHPPKSKD
     301  IYPYESKKPK SKRLQQAMKF CQSVLKELMA KKHASYNYPF LEPVDPVSMN
     351  LPTYFDYVKE PMDLGTIAKK LNDWQYQTME DFERDVRLVF KNCYTFNPDG
     401  TIVNMMGHRL EEVFNSKWAD RPNLDDYDSD EDSRTQGDYD DYESEYSESD
     451  IDETIITNPA IQYLEEQLAR MKVELQQLKK QELEKIRKER RLARGSKKRG
     501  KRSKGRSGSK NASSKGRRDK KNKLKTVVTY DMKRIITERI NDLPTSKLER
     551  AIDIIKKSMP NISEDDEVEL DLDTLDNHTI LTLYNTFFRQ YESSSGASNG
     601  LDGTSGVTRD ASSLSPTSAG SRKRRSKALS QEEQSRQIEK IKNKLAILDS
     651  ASPLSQNGSP GQIQSAAHNG FSSSSDDDVS SESEEE*              

external links for Bdf1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Bdf1p
1) Lygerou Z, et al.  (1994) The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs. Nucleic Acids Res 22(24):5332-40
2) Matangkasombut O, et al.  (2000) Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. Genes Dev 14(8):951-62
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41