TAL1/YLR354C Protein Information

Standard Name	Tal1p 1
Systematic Name	Ylr354cp
ORF Classification	Verified
Description	Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate; TAL1 has a paralog, NQM1, that arose from the whole genome duplication (1, 2)
Name Description	TransALdolase 1

Experimental Data
Molecules/cell	53000 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	335
Molecular Weight (Da)	37,036
Isoelectric Point (pI)	6.36

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Tal1p (InterPro)
Physical Interactions	There are 22 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001683AB \| P15019 MIPS: YLR354C NCBI: 1729825 \| 3828 \| 4602 \| 609402 \| 6323386 \| 736725 \| NP_013458.1 GenBank/EMBL/DDBJ: DAA09658.1 \| L37016 \| U19102 \| X04969 \| X15953
External Classifications	EC: 2.2.1.2 [Transaldolase]

Amino Acid Sequence (or in FASTA format)
1 MSEPAQKKQK VANNSLEQLK ASGTVVVADT GDFGSIAKFQ PQDSTTNPSL 51 ILAAAKQPTY AKLIDVAVEY GKKHGKTTEE QVENAVDRLL VEFGKEILKI 101 VPGRVSTEVD ARLSFDTQAT IEKARHIIKL FEQEGVSKER VLIKIASTWE 151 GIQAAKELEE KDGIHCNLTL LFSFVQAVAC AEAQVTLISP FVGRILDWYK 201 SSTGKDYKGE ADPGVISVKK IYNYYKKYGY KTIVMGASFR STDEIKNLAG 251 VDYLTISPAL LDKLMNSTEP FPRVLDPVSA KKEAGDKISY ISDESKFRFD 301 LNEDAMATEK LSEGIRKFSA DIVTLFDLIE KKVTA*

Amino Acid Sequence (or in FASTA format)

       1  MSEPAQKKQK VANNSLEQLK ASGTVVVADT GDFGSIAKFQ PQDSTTNPSL
      51  ILAAAKQPTY AKLIDVAVEY GKKHGKTTEE QVENAVDRLL VEFGKEILKI
     101  VPGRVSTEVD ARLSFDTQAT IEKARHIIKL FEQEGVSKER VLIKIASTWE
     151  GIQAAKELEE KDGIHCNLTL LFSFVQAVAC AEAQVTLISP FVGRILDWYK
     201  SSTGKDYKGE ADPGVISVKK IYNYYKKYGY KTIVMGASFR STDEIKNLAG
     251  VDYLTISPAL LDKLMNSTEP FPRVLDPVSA KKEAGDKISY ISDESKFRFD
     301  LNEDAMATEK LSEGIRKFSA DIVTLFDLIE KKVTA*

external links for Tal1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Tal1p

1)	Schaaff I, et al. (1990) Molecular analysis of the structural gene for yeast transaldolase. Eur J Biochem 188(3):597-603
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41