YLR345W Protein Information Help

Systematic Name Ylr345wp
ORF Classification Uncharacterized
Description Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene (1, 2)
Experimental Data
Molecules/cell 3380 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 509
Molecular Weight (Da) 58,385
Isoelectric Point (pI) 6.41

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ylr345wp (InterPro)
Physical Interactions There are 33 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006AAC5 | Q06137
MIPS: YLR345W
NCBI: 609382 | 6323377 | 74644936 | NP_013449.1
GenBank/EMBL/DDBJ: DAA09650.1 | U19028
External Classifications EC: 2.7.1.105 [6-phosphofructo-2-kinase]
EC: 3.1.3.46 [Fructose-2,6-bisphosphate 2-phosphatase]
Amino Acid Sequence (or in FASTA format)
 
       1  MPNVLSDDEE LLNGLGSEIM KPSRQGNHMA RTVKRWVNKE RATTADLKNV
      51  NIDGVHGPVN TESYISPGQL YSTDSGNLFH AGRILVVLVG LPATSKTLLS
     101  VAITRYTRWL GVRTKSFHFS EYKESAKNIP SDYFCVVPTS KEGVAFVEKL
     151  RMQMLNDILA FFNDLSGQLA IYDALNIRKI DRKNLETTFS EIGVKVLFIE
     201  SIVSDQEIMN RNIALALESN DYKGLSTDEA IDEYMRRLSV NEPYYEMMTH
     251  DEELSYIKYI NLGKQIIVKD NIHGYLVNKI VFFLMNLRQK KGCVYFARCG
     301  TSDKDNYIHD EELNEEGIHY SQVLKDFVLQ RIKQKRQAKK NSDSLVEVID
     351  GSHDEDLKTS LIVWTGPRKR THDTALFFSK EGIKVQQRSE LRQLNPGSIA
     401  DLTDQQIMDK FPSEYKESLK DPYHFRFPRA ESYHDLAVRM EPLLLEMEHT
     451  SKDILIIAHE STLRVLYGYL MACTCVELPN LNFTRDKLVE ISFSPFCNTV
     501  ELLNIPLTS*

external links for Ylr345wp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Ylr345wp
1) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2) Zaim J, et al.  (2005) Identification of new genes regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae. J Biol Chem 280(1):28-37
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41