CHS5/YLR330W Protein Information Help

Standard Name Chs5p
Systematic Name Ylr330wp
Alias Cal3p
ORF Classification Verified
Description Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane (1, 2, 3, 4, 5)
Name Description CHitin Synthase-related 3
Experimental Data
Molecules/cell 172 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 671
Molecular Weight (Da) 73,638
Isoelectric Point (pI) 4.33

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Chs5p (InterPro)
Physical Interactions There are 67 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000127929 | Q12114
MIPS: YLR330W
NCBI: 1297018 | 2498236 | 409107320 | 459358918 | 459358920 | 6323362 | 662142 | NP_013434.1
GenBank/EMBL/DDBJ: DAA09638.1 | U20618 | Z49198
Amino Acid Sequence (or in FASTA format)
 
       1  MSSVDVLLTV GKLDASLALL TTQDHHVIEF PTVLLPENVK AGSIIKMQVS
      51  QNLEEEKKQR NHFKSIQAKI LEKYGTHKPE SPVLKIVNVT QTSCVLAWDP
     101  LKLGSAKLKS LILYRKGIRS MVIPNPFKVT TTKISGLSVD TPYEFQLKLI
     151  TTSGTLWSEK VILRTHKMTD MSGITVCLGP LDPLKEISDL QISQCLSHIG
     201  ARPLQRHVAI DTTHFVCNDL DNEESNEELI RAKHNNIPIV RPEWVRACEV
     251  EKRIVGVRGF YLDADQSILK NYTFPPVNEE ELSYSKENEP VAEVADENKM
     301  PEDTTDVEQV ASPNDNESNP SEAKEQGEKS GHETAPVSPV EDPLHASTAL
     351  ENETTIETVN PSVRSLKSEP VGTPNIEENK ADSSAEAVVE EPNEAVAESS
     401  PNEEATGQKS EDTDTHSNEQ ADNGFVQTEE VAENNITTES AGENNEPADD
     451  AAMEFGRPEA EIETPEVNES IEDANEPAED SNEPVEDSNK PVKDSNKPVE
     501  DSNKPVEDSN KPVEDSNKPV EDANEPVEDT SEPVEDAGEP VQETNEFTTD
     551  IASPRHQEED IELEAEPKDA TESVAVEPSN EDVKPEEKGS EAEDDINNVS
     601  KEAASGESTT HQKTEASASL ESSAVTEEQE TTEAEVNTDD VLSTKEAKKN
     651  TGNSNSNKKK NKKNKKKGKK K*

external links for Chs5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Chs5p
1) Santos B, et al.  (1997) CHS5, a gene involved in chitin synthesis and mating in Saccharomyces cerevisiae. Mol Cell Biol 17(5):2485-96
2) Santos B and Snyder M  (1997) Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p. J Cell Biol 136(1):95-110
3) Cid VJ, et al.  (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86
4) Trautwein M, et al.  (2006) Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi. EMBO J 25(5):943-54
5) Wang CW, et al.  (2006) Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast. J Cell Biol 174(7):973-83
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41