UBC12/YLR306W Protein Information

Standard Name	Ubc12p
Systematic Name	Ylr306wp
ORF Classification	Verified
Description	Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes (1)
Name Description	UBiquitin-Conjugating

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	188
Molecular Weight (Da)	21,203
Isoelectric Point (pI)	5.44

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ubc12p (InterPro)
Physical Interactions	There are 12 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000137971 \| P52491 MIPS: YLR306W NCBI: 1480353 \| 1717863 \| 306991903 \| 306991904 \| 358009677 \| 358009678 \| 577219 \| 6323337 \| NP_013409.1 GenBank/EMBL/DDBJ: DAA09615.1 \| U17247 \| X99442
External Classifications	EC: 6.3.2.- [Acid-Amino-Acid Ligases (Peptide Synthases)]

Amino Acid Sequence (or in FASTA format)
1 MLKLRQLQKK KQKENENSSS IQPNLSAARI RLKRDLDSLD LPPTVTLNVI 51 TSPDSADRSQ SPKLEVIVRP DEGYYNYGSI NFNLDFNEVY PIEPPKVVCL 101 KKIFHPNIDL KGNVCLNILR EDWSPALDLQ SIITGLLFLF LEPNPNDPLN 151 KDAAKLLCEG EKEFAEAVRL TMSGGSIEHV KYDNIVSP*

Amino Acid Sequence (or in FASTA format)

       1  MLKLRQLQKK KQKENENSSS IQPNLSAARI RLKRDLDSLD LPPTVTLNVI
      51  TSPDSADRSQ SPKLEVIVRP DEGYYNYGSI NFNLDFNEVY PIEPPKVVCL
     101  KKIFHPNIDL KGNVCLNILR EDWSPALDLQ SIITGLLFLF LEPNPNDPLN
     151  KDAAKLLCEG EKEFAEAVRL TMSGGSIEHV KYDNIVSP*

external links for Ubc12p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ubc12p

1)	Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14