CTS1/YLR286C Protein Information

Standard Name	Cts1p
Systematic Name	Ylr286cp
ORF Classification	Verified
Description	Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p (1, 2, 3)
Name Description	ChiTinaSe

Experimental Data
Molecules/cell	6350 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	562
Molecular Weight (Da)	59,014
Isoelectric Point (pI)	4.22

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Cts1p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000127831 \| P29029 MIPS: YLR286C NCBI: 146387178 \| 146387179 \| 146387180 \| 146387181 \| 1705815 \| 171332 \| 171334 \| 51013531 \| 596043 \| 6323316 \| NP_013388.1 GenBank/EMBL/DDBJ: DAA09597.1 \| AY693040 \| M74069 \| M74070 \| U17243
External Classifications	EC: 3.2.1.14 [Chitinase]

Amino Acid Sequence (or in FASTA format)
1 MSLLYIILLF TQFLLLPTDA FDRSANTNIA VYWGQNSAGT QESLATYCES 51 SDADIFLLSF LNQFPTLGLN FANACSDTFS DGLLHCTQIA EDIETCQSLG 101 KKVLLSLGGA SGSYLFSDDS QAETFAQTLW DTFGEGTGAS ERPFDSAVVD 151 GFDFDIENNN EVGYSALATK LRTLFAEGTK QYYLSAAPQC PYPDASVGDL 201 LENADIDFAF IQFYNNYCSV SGQFNWDTWL TYAQTVSPNK NIKLFLGLPG 251 SASAAGSGYI SDTSLLESTI ADIASSSSFG GIALWDASQA FSNELNGEPY 301 VEILKNLLTS ASQTATTTVA TSKTSAASTS SASTSSASTS QKKTTQSTTS 351 TQSKSKVTLS PTASSAIKTS ITQTTKTLTS STKTKSSLGT TTTESTLNSV 401 AITSMKTTLS SQITSAALVT PQTTTTSIVS SAPIQTAITS TLSPATKSSS 451 VVSLQTATTS TLSPTTTSTS SGSTSSGSTS SDSTARTLAK ELNAQYAAGK 501 LNGKSTCTEG EIACSADGKF AVCDHSAWVY MECASGTTCY AYDSGDSVYT 551 QCNFSYLESN YF*

Amino Acid Sequence (or in FASTA format)

       1  MSLLYIILLF TQFLLLPTDA FDRSANTNIA VYWGQNSAGT QESLATYCES
      51  SDADIFLLSF LNQFPTLGLN FANACSDTFS DGLLHCTQIA EDIETCQSLG
     101  KKVLLSLGGA SGSYLFSDDS QAETFAQTLW DTFGEGTGAS ERPFDSAVVD
     151  GFDFDIENNN EVGYSALATK LRTLFAEGTK QYYLSAAPQC PYPDASVGDL
     201  LENADIDFAF IQFYNNYCSV SGQFNWDTWL TYAQTVSPNK NIKLFLGLPG
     251  SASAAGSGYI SDTSLLESTI ADIASSSSFG GIALWDASQA FSNELNGEPY
     301  VEILKNLLTS ASQTATTTVA TSKTSAASTS SASTSSASTS QKKTTQSTTS
     351  TQSKSKVTLS PTASSAIKTS ITQTTKTLTS STKTKSSLGT TTTESTLNSV
     401  AITSMKTTLS SQITSAALVT PQTTTTSIVS SAPIQTAITS TLSPATKSSS
     451  VVSLQTATTS TLSPTTTSTS SGSTSSGSTS SDSTARTLAK ELNAQYAAGK
     501  LNGKSTCTEG EIACSADGKF AVCDHSAWVY MECASGTTCY AYDSGDSVYT
     551  QCNFSYLESN YF*

external links for Cts1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Cts1p

1)	O'Conallain C, et al. (1999) Regulated nuclear localisation of the yeast transcription factor Ace2p controls expression of chitinase (CTS1) in Saccharomyces cerevisiae. Mol Gen Genet 262(2):275-82
2)	Kuranda MJ and Robbins PW (1991) Chitinase is required for cell separation during growth of Saccharomyces cerevisiae. J Biol Chem 266(29):19758-67
3)	Dohrmann PR, et al. (1992) Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev 6(1):93-104
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41