YLR253W Protein Information

Systematic Name	Ylr253wp
ORF Classification	Uncharacterized
Description	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; transcription is periodic during the metabolic cycle; YLR253W is not an essential gene (1, 2, 3, 4)

Experimental Data
Molecules/cell	1600 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	569
Molecular Weight (Da)	65,917
Isoelectric Point (pI)	9.45

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ylr253wp (InterPro)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B7CE \| Q06567 MIPS: YLR253W NCBI: 3025214 \| 6323282 \| 662332 \| NP_013354.1 GenBank/EMBL/DDBJ: DAA09566.1 \| U20865

Amino Acid Sequence (or in FASTA format)
1 MMTKAFFNKL PFEVFRRYVR TGKSIPQRSP RTRKSLLVGG TIASAVVLYN 51 FNDTFHDSVK HTALTTKRIA VVTQATTRCF YHYKRALNKS YENKKEREVA 101 LNKCHKMCAL ITLHALRSNG GIYIKLGQHI GAMTYLLPKE WTDTMIPLQD 151 HCPESTYEEI DELFKEDLGT SIEDMFLEFN KTPIGVASLA QVHVAKLKNS 201 DGKGSSVAVK CQHPSLKEFI PLDVMLTRTV FELLDVFFPD YPLTWLGDEL 251 QSSIYVELNF TKEAENAEKT RHYFSKFKKQ TALKIPKVIE SHKRILIMEY 301 VGGKRLDDLE YIDSHGISRS EVSSCLSHIF NNMIFTPNVG IHCDPHGGNL 351 AIRSVKPAKD NGYHNFEIVL FDHGLYRYPS TRTRRLYAKF WLSLLFDKDQ 401 TKMKKYAKGF ANITDEQFPL LAAAITGRSI DAALNYDIST SRTQEEMDVM 451 ANGILEGTLL SDLMSILSRI PRVVLLILKT NDLTRHLDEC LQNPLGPERT 501 FLIMTQYCAK TVYDEKVERI NSEYARWSIK WMWENLTNWI VYERRINQLY 551 FYDFVLWWKK FIPKTWLSS*

Amino Acid Sequence (or in FASTA format)

       1  MMTKAFFNKL PFEVFRRYVR TGKSIPQRSP RTRKSLLVGG TIASAVVLYN
      51  FNDTFHDSVK HTALTTKRIA VVTQATTRCF YHYKRALNKS YENKKEREVA
     101  LNKCHKMCAL ITLHALRSNG GIYIKLGQHI GAMTYLLPKE WTDTMIPLQD
     151  HCPESTYEEI DELFKEDLGT SIEDMFLEFN KTPIGVASLA QVHVAKLKNS
     201  DGKGSSVAVK CQHPSLKEFI PLDVMLTRTV FELLDVFFPD YPLTWLGDEL
     251  QSSIYVELNF TKEAENAEKT RHYFSKFKKQ TALKIPKVIE SHKRILIMEY
     301  VGGKRLDDLE YIDSHGISRS EVSSCLSHIF NNMIFTPNVG IHCDPHGGNL
     351  AIRSVKPAKD NGYHNFEIVL FDHGLYRYPS TRTRRLYAKF WLSLLFDKDQ
     401  TKMKKYAKGF ANITDEQFPL LAAAITGRSI DAALNYDIST SRTQEEMDVM
     451  ANGILEGTLL SDLMSILSRI PRVVLLILKT NDLTRHLDEC LQNPLGPERT
     501  FLIMTQYCAK TVYDEKVERI NSEYARWSIK WMWENLTNWI VYERRINQLY
     551  FYDFVLWWKK FIPKTWLSS*

external links for Ylr253wp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Ylr253wp

1)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3)	Tu BP, et al. (2005) Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science 310(5751):1152-8
4)	Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41