YLR149C Protein Information Help

Systematic Name Ylr149cp
ORF Classification Verified
Description Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutation results in a decrease in plasma membrane electron transport; YLR149C is not an essential gene; protein abundance increases in response to DNA replication stress (1, 2, 3, 4, 5)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 730
Molecular Weight (Da) 82,799
Isoelectric Point (pI) 6.32

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ylr149cp (InterPro)
Physical Interactions There are 3 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006A8C6 | Q99296
MIPS: YLR149C
NCBI: 1262309 | 1360578 | 6323178 | 74698029 | NP_013250.1
GenBank/EMBL/DDBJ: DAA09460.1 | U53879 | Z73321
Amino Acid Sequence (or in FASTA format)
 
       1  MTIDGTGQSK EALQDERLNT GSDKVYQNYM MPALELYDAK VSINHWQLRD
      51  CIKPGSMNQS KLYYIYDHSI RVLDTDSSVL RSPVRRHNSI QPSNSGKNST
     101  EKTSTKGSRT TGSYISKNLH VPSEKLVEFN FKPRCFTELN GLTVCGGLIG
     151  SDDKGFPSNW NRLAQDANIS LPPPSQPINI SKNISFPINS HYSNPNIWKG
     201  IVEFYNQETD TMMTFTLGQF INNCVTLYDR ASMQFDLFAC NNDGHLYQCD
     251  VSNRDVTLVK RYADLKFPLN NASLSHDGQT MVVSGDSNKF AVYNQNELTN
     301  QFSLHYDNHP SWGSSVNRVR RIPRFALPDE SEYIENIYEA PNSDHGFYNS
     351  FSENDLQFAT VFQNGTCAIY DIRNMATPMA EISSTRPHSH NGAFRVCRFS
     401  YGLDDLLFIS EHQGRVHVVD TRNYVNHQVI VIPDKVNMEY INERKHNTNH
     451  NFTTNNNNEN ESNDSKNELQ GADYRSLSRR RFSLPSMPNV TTEPWITMAQ
     501  RIPKKYLEPQ ILPFPKVMDK ISNESVLFST KGSSSSDVAH PYKRRCSFRV
     551  RRVSTSAPTA DYSNNNVNAS LGTPAADSIA TSSSNSAPQN LIDPLILSHQ
     601  QASNDVFEDD EYYEAYNDVH STYRVSSDYH GVSARAFESF LRPPSTPDLP
     651  SDDDNFAANS RNNRGTSNFL RRPVITTQES NEFSEENNIS GIDWVEDRNG
     701  SSLIIGTDYG IMRWNINSWA RRSFSSYDLC *

external links for Ylr149cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ylr149cp
1) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Niu W, et al.  (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120
4) Herst PM, et al.  (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
5) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76