CCW12/YLR110C Protein Information Help

Standard Name Ccw12p 1
Systematic Name Ylr110cp
ORF Classification Verified
Description Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Covalently linked Cell Wall protein 1
Experimental Data
Molecules/cell 158000 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 133
Molecular Weight (Da) 13,057
Isoelectric Point (pI) 4.38

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ccw12p (InterPro)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 13 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000004F946 | Q12127
MIPS: YLR110C
NCBI: 1256873 | 1360502 | 2498096 | 45269749 | 6323139 | NP_013211.1
GenBank/EMBL/DDBJ: DAA09426.1 | AY557929 | U53878 | Z73282
Amino Acid Sequence (or in FASTA format)
 
       1  MQFSTVASIA AVAAVASAAA NVTTATVSQE STTLVTITSC EDHVCSETVS
      51  PALVSTATVT VDDVITQYTT WCPLTTEAPK NGTSTAAPVT STEAPKNTTS
     101  AAPTHSVTSY TGAAAKALPA AGALLAGAAA LLL*

external links for Ccw12p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome


DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Ccw12p
1) Mrsa V, et al.  (1999) Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae. J Bacteriol 181(10):3076-86
2) Seidel J and Tanner W  (1997) Characterization of two new genes down-regulated by alpha-factor. Yeast 13(9):809-17
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Ragni E, et al.  (2011) The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections. BMC Genomics 12():107
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41