REX3/YLR107W Protein Information

Standard Name	Rex3p 1
Systematic Name	Ylr107wp
ORF Classification	Verified
Description	RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases (1)
Name Description	Rna EXonuclease 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	404
Molecular Weight (Da)	45,879
Isoelectric Point (pI)	9.2

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rex3p (InterPro)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006C5E6 \| Q12090 MIPS: YLR107W NCBI: 1256855 \| 1297021 \| 1360496 \| 2204275 \| 2341001 \| 6323136 \| 74676521 \| NP_013208.1 GenBank/EMBL/DDBJ: DAA09423.1 \| U53876 \| U53878 \| X89514 \| Z73279 \| Z73280
External Classifications	EC: 3.1.-.- [Hydrolases acting on ester bonds ]

Amino Acid Sequence (or in FASTA format)
1 MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT 51 RLEVHVAKNS LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH 101 LSSIGNANSI TTKSKAMEAL KALILDSKVL EKNGYIVKEM QNKTNDDNST 151 QLYAPCLRCS SNFKKTDIME KTLCRYHPLK RIYNRDTKNH QYPCCGETTD 201 SVSFLRLGCK TFFHHVFRGE SYDELCKISK FSSTDDIDGV ENVLSLDCEM 251 AFTSLGYEMI RLTIVDFFTG KTLFDHVIQP IGDIVDLNSD FSGVHEIDRT 301 NCPTYKEALD VFLSENLINK NSILIGHGLE NDLNVMRLFH NKVIDTAILY 351 SRTKFKVSLK NLAFEVLSRK IQNGEHDSSQ DAIATMDVVK VKIGISPSQN 401 KWEK*

Amino Acid Sequence (or in FASTA format)

       1  MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT
      51  RLEVHVAKNS LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH
     101  LSSIGNANSI TTKSKAMEAL KALILDSKVL EKNGYIVKEM QNKTNDDNST
     151  QLYAPCLRCS SNFKKTDIME KTLCRYHPLK RIYNRDTKNH QYPCCGETTD
     201  SVSFLRLGCK TFFHHVFRGE SYDELCKISK FSSTDDIDGV ENVLSLDCEM
     251  AFTSLGYEMI RLTIVDFFTG KTLFDHVIQP IGDIVDLNSD FSGVHEIDRT
     301  NCPTYKEALD VFLSENLINK NSILIGHGLE NDLNVMRLFH NKVIDTAILY
     351  SRTKFKVSLK NLAFEVLSRK IQNGEHDSSQ DAIATMDVVK VKIGISPSQN
     401  KWEK*

external links for Rex3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Rex3p

1)	van Hoof A, et al. (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19(6):1357-65