APC9/YLR102C Protein Information

Standard Name	Apc9p 1
Systematic Name	Ylr102cp
ORF Classification	Verified
Description	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition (1, 2)
Name Description	Anaphase Promoting Complex 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	265
Molecular Weight (Da)	30,856
Isoelectric Point (pI)	5.34

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Apc9p (InterPro)
Physical Interactions	There are 50 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006BA3D \| Q12107 MIPS: YLR102C NCBI: 1256851 \| 1360486 \| 55976293 \| 6323131 \| NP_013203.1 GenBank/EMBL/DDBJ: DAA09418.1 \| U53876 \| Z73274

Amino Acid Sequence (or in FASTA format)
1 MNQNGDKNEG KLFQLPSLPP WKTPRFNKAN FNNFTTPLRK RSTRVINDDS 51 MPITGEVLEE RTADDLYGIN MDVDEVDYLN TLSHIEEEKQ YDYSPFCERN 101 TLRESRIDSF LKAERAAHCL VFHKVGHLDG IDSYRPDIDI MCGEEANKYD 151 SANPEGNGSM LLESVPGCNK EDLERLSRRE FVTNSKPNMR RLDDIINHET 201 NALKSFWNDS GLVNSLQSHH LHEEYLLLQE ELKNVYKIKC HDRVPIESLR 251 DKCRRHYSNE DSSFL*

Amino Acid Sequence (or in FASTA format)

       1  MNQNGDKNEG KLFQLPSLPP WKTPRFNKAN FNNFTTPLRK RSTRVINDDS
      51  MPITGEVLEE RTADDLYGIN MDVDEVDYLN TLSHIEEEKQ YDYSPFCERN
     101  TLRESRIDSF LKAERAAHCL VFHKVGHLDG IDSYRPDIDI MCGEEANKYD
     151  SANPEGNGSM LLESVPGCNK EDLERLSRRE FVTNSKPNMR RLDDIINHET
     201  NALKSFWNDS GLVNSLQSHH LHEEYLLLQE ELKNVYKIKC HDRVPIESLR
     251  DKCRRHYSNE DSSFL*

external links for Apc9p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Apc9p

1)	Zachariae W, et al. (1998) Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science 279(5354):1216-9
2)	Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58