IOC2/YLR095C Protein Information Help

Standard Name Ioc2p 1
Systematic Name Ylr095cp
ORF Classification Verified
Description Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif (1, 2)
Name Description Iswi One Complex 1
Experimental Data
Molecules/cell 7520 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 812
Molecular Weight (Da) 93,445
Isoelectric Point (pI) 5.58

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ioc2p (InterPro)
Physical Interactions There are 17 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000069787 | Q12072
MIPS: YLR095C
NCBI: 1256845 | 1360473 | 6323124 | 74645020 | NP_013196.1
GenBank/EMBL/DDBJ: DAA09411.1 | U53876 | Z73267
Amino Acid Sequence (or in FASTA format)
 
       1  MRTKRTRGTR NVGASMPAGA ANADSEDWKE YVSEDIIAQL NKHQLPYSEI
      51  LDEKIADLAN HWHFQYVMAW LSNVCESYTT TTFNTDQYGG SSTKCLWKNI
     101  KFDEGVFVTD VFSKIDGKDS NYYNDEVDVD EGSQNLYDRI RLQLLHQLAG
     151  NKSGQLKDWN VIVNHHLQNS SAYSDLVTDL PFLELEIARQ FDIIYSIIKL
     201  IEMKNMIFKN YLANNLHLFT FSEVILDDDN SGGEEMKSLF ALPNVGVLVK
     251  KTIHRVKEGS SSQVSQTLNI PIKLQNCTIK ESDPDIPDSV ELIHLEYSHD
     301  IDAYLQSITI DYDVITTNWG SMLEYWSENK SSKAIDEFIT NLIPVYAEHR
     351  LYSAKLLANR EKERAIAELM TRRKRSSRLV AKEEENKKKD LESEWFEKLD
     401  EREQFIRHRN KLVSKEIKKI KDLLWNQLWQ LYDQDYRDEK LTRRNELKDR
     451  SGSGTPFFET SLGREEDNPL NEIDIGVLDH GPNFQSSIIP VEPPIPGTVG
     501  PLQTGDVPEL PSDFCITKEE LDELANYGIF TPQQEPDNQD SVFQCPGEPE
     551  LAPMIITEDT ETDLFNNRPL ICCDHCYRWQ HWECQPPKII ELISSTTKSP
     601  QHTLSQRDFG VIIMGNSHGN RRSSRRPQST LEPSTKSSRP TDKRKPLSEC
     651  STFICAWCIR DLELELRNIF VPELKIIRAK QRKQQEDRER RKKMKEEKKR
     701  LEELAKKREL TESVSPPVFN NAFANMSSST TPSIAAYEKT NPAINPAPNV
     751  NAAHPIITYS QQTGSKTVPQ APQAPQTSQA SIQPQQQQQQ QQQQQPLHPK
     801  EQNFHFQFPP TN*

external links for Ioc2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ioc2p
1) Vary JC Jr, et al.  (2003) Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol 23(1):80-91
2) Morillon A, et al.  (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115(4):425-35
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41