ARP6/YLR085C Protein Information

Standard Name	Arp6p 1
Systematic Name	Ylr085cp
ORF Classification	Verified
Description	Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A (1, 2)
Name Description	Actin-Related Protein 1

Experimental Data
Molecules/cell	238 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	438
Molecular Weight (Da)	50,043
Isoelectric Point (pI)	5.31

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Arp6p (InterPro)
Physical Interactions	There are 39 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000126062 \| Q12509 MIPS: YLR085C NCBI: 1256887 \| 1360453 \| 2492676 \| 6323114 \| NP_013186.1 \| NM_001181972.1 GenBank/EMBL/DDBJ: DAA09401.1 \| U53880 \| Z73257

Amino Acid Sequence (or in FASTA format)
1 METPPIVIDN GSYEIKFGPS TNKKPFRALN ALAKDKFGTS YLSNHIKNIK 51 DISSITFRRP HELGQLTLWE LESCIWDYCL FNPSEFDGFD LKEGKGHHLV 101 ASESCMTLPE LSKHADQVIF EEYEFDSLFK SPVAVFVPFT KSYKGEMRTI 151 SGKDEDIDIV RGNSDSTNST SSESKNAQDS GSDYHDFQLV IDSGFNCTWI 201 IPVLKGIPYY KAVKKLDIGG RFLTGLLKET LSFRHYNMMD ETILVNNIKE 251 QCLFVSPVSY FDSFKTKDKH ALEYVLPDFQ TSFLGYVRNP RKENVPLPED 301 AQIITLTDEL FTIPETFFHP EISQITKPGI VEAILESLSM LPEIVRPLMV 351 GNIVCTGGNF NLPNFAQRLA AELQRQLPTD WTCHVSVPEG DCALFGWEVM 401 SQFAKTDSYR KARVTREEYY EHGPDWCTKH RFGYQNWI*

Amino Acid Sequence (or in FASTA format)

       1  METPPIVIDN GSYEIKFGPS TNKKPFRALN ALAKDKFGTS YLSNHIKNIK
      51  DISSITFRRP HELGQLTLWE LESCIWDYCL FNPSEFDGFD LKEGKGHHLV
     101  ASESCMTLPE LSKHADQVIF EEYEFDSLFK SPVAVFVPFT KSYKGEMRTI
     151  SGKDEDIDIV RGNSDSTNST SSESKNAQDS GSDYHDFQLV IDSGFNCTWI
     201  IPVLKGIPYY KAVKKLDIGG RFLTGLLKET LSFRHYNMMD ETILVNNIKE
     251  QCLFVSPVSY FDSFKTKDKH ALEYVLPDFQ TSFLGYVRNP RKENVPLPED
     301  AQIITLTDEL FTIPETFFHP EISQITKPGI VEAILESLSM LPEIVRPLMV
     351  GNIVCTGGNF NLPNFAQRLA AELQRQLPTD WTCHVSVPEG DCALFGWEVM
     401  SQFAKTDSYR KARVTREEYY EHGPDWCTKH RFGYQNWI*

external links for Arp6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Arp6p

1)	Poch O and Winsor B (1997) Who's who among the Saccharomyces cerevisiae actin-related proteins? A classification and nomenclature proposal for a large family. Yeast 13(11):1053-8
2)	Wu WH, et al. (2005) Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange. Nat Struct Mol Biol 12(12):1064-71
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41