RAX2/YLR084C Protein Information Help

Standard Name Rax2p 1
Systematic Name Ylr084cp
ORF Classification Verified
Description N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p (1, 2, 3)
Experimental Data
Molecules/cell 3670 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,220
Molecular Weight (Da) 133,958
Isoelectric Point (pI) 4.26

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rax2p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 14 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006B494 | Q12465
MIPS: YLR084C
NCBI: 1256886 | 1360451 | 6323113 | 74645058 | NP_013185.1
GenBank/EMBL/DDBJ: DAA09400.1 | U53880 | Z73256
Amino Acid Sequence (or in FASTA format)
 
       1  MFVHRLWTLA FPFLVEISKA SQLENIKSLL DIEDNVLPNL NISQNNSNAV
      51  QILGGVDALS FYEYTGQQNF TKEIGPETSS HGLVYYSNNT YIQLEDASDD
     101  TRIDKITPFG VDSFILSGSG TINNISVGNQ ILYNLSTLSM TPIFNQSLGA
     151  VQAVLADNSS IYFGGNFSYN NGSMTGYSAL IWDSISNTTQ LLPFGGFGEN
     201  SSVNSIVKLN NDNILFAGQF YTLDDPSALI SSSNNGTNST SSLNATTLEL
     251  GQRIPLRYAS WDSQGSTTFA SDSLVCPNTN EDAWLYPDTS GSLVCNLPYE
     301  VSPTKIRLYN SQRSDSEISV FQILTDPSSS IMNLTYLDPL SGELKNCGEF
     351  CPLYSRATLL SASQNVSSSM DMITFIDNNK TDVKWTSDFQ DFAFVNELPV
     401  SSLKFVALNS YGGSVGLSGL ELYQDTFSTY ANDSLNEYGC SALTNDSSSS
     451  TLSSNDWYNG LTGESYIAAK YVPDQNEPIP RVKFYPNIIH PGHYTINMYT
     501  PGCLQDNTCS ARGIVNVTMW NQQNNTIMKT YLIYQNNDNL KYDQIYSGYL
     551  DFSPEIVLEY VSGIYTTNTA TVVVADQVNV ITVSLDAFNT LSDSSNAKKE
     601  TLLNGILQYQ KSNFTSTRLN ETKVGNTTLN LFPVKNYPKN SSLYADIYDN
     651  KLVIGGVSNR ISIVDLNDDF EVTSSKNQTI QGDVHGITKT NQGLLIFGDI
     701  LSSNNQSAVF LFNGSFENVF NQSRTVNSAL NISLANNDFI VLDNDYVVNA
     751  SSNALIRNSS SFSLSLWAAG NNGDGDVLFS GAVSHMQYGN LNGSVRFLNE
     801  NEIEPLNLEG GIVPYLGAYL NESATAYAYE VDSLNKIYFS NEVYPSWNWS
     851  SGITQMLYAD NQTLLAVSAG SSTTAELSIF DLRNLTMIAN ETLGSNARIN
     901  ALVNFEKNCS MLVGGDFQMT EPNCTGLCLY NYESKTWSTF LNNTIFGEIT
     951  QLSFTNSSEL IISGLFETKE YQSIRLGSFN LTNSTMIPLL SGSEGKLNSF
    1001  TVTEDSIVAW NDTSLFIYRN QEWNITSLPG NASSISSVSA IYTDIESNTL
    1051  NKRGINNVNN GSILLLNGNF NISQYGYLQS LLFDFQKWTP YFISETTNTS
    1101  NYNPIIFINR DVSTEFNSQS PLANVNITVT SPQSTSSQPP SSSASSESKS
    1151  KSKKKKIGRG FVVLIGLALA LGTVSVLGIA GVILAYVFKD PEGDYKPIKP
    1201  RIDENEMLDT VPPEKLMKFV *

external links for Rax2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome

YGOB GeneMANIA

YOGY


References cited on this page View Complete Literature Guide for Rax2p
1) Chen T, et al.  (2000) Multigenerational cortical inheritance of the Rax2 protein in orienting polarity and division in yeast. Science 290(5498):1975-8
2) Kang PJ, et al.  (2004) Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast. Mol Biol Cell 15(11):5145-57
3) Seay D, et al.  (2006) A three-hybrid screen identifies mRNAs controlled by a regulatory protein. RNA 12(8):1594-600
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41