SRL2/YLR082C Protein Information

Standard Name	Srl2p
Systematic Name	Ylr082cp
ORF Classification	Verified
Description	Protein of unknown function; overexpression suppresses the lethality caused by a rad53 null mutation (1)
Name Description	Suppressor of Rad53 null Lethality 1

Experimental Data
Molecules/cell	538 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	392
Molecular Weight (Da)	45,140
Isoelectric Point (pI)	7.99

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Srl2p (InterPro)
Physical Interactions	There are 22 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006C686 \| Q12020 MIPS: YLR082C NCBI: 1256884 \| 1360447 \| 6323111 \| 74645018 \| NP_013183.1 GenBank/EMBL/DDBJ: DAA09398.1 \| U53880 \| Z73254

Amino Acid Sequence (or in FASTA format)
1 MSNFKNFTLN SFEDYYGKPS ETPKMEEEKL EVTNVNASSS KKVHKSKKST 51 SKYDQKNVFR NSMTGIAQIL PTKPVKIIEQ NIDFANPKSF DLLQSTHTIC 101 FNKRINTTNT KLNVETHTSS DIDNDILHVG APTDLGGNSN DEAETRQLRK 151 FRWSNNKEKS LCEKLTVIYW ALLLHTTKRA SKRRPILCHQ MIAEFFNRVY 201 KEKSRVPITS RYIRDNLVAW VTQGKELHEK GWVGDAKTGD LQEQFNIATV 251 KLYESAEDGR LSIGKDKPFR EENTGSDSLV RAEEDSTAVT NENGHISSEK 301 NLKKDRRESI RNQILTLDLN DEDFFQNVMK VLSAIDEPEL RQYVIVISEL 351 VSMEMDDGKT VREKLRDVEL NINRLQVDIK EIKEMLVTLI NK*

Amino Acid Sequence (or in FASTA format)

       1  MSNFKNFTLN SFEDYYGKPS ETPKMEEEKL EVTNVNASSS KKVHKSKKST
      51  SKYDQKNVFR NSMTGIAQIL PTKPVKIIEQ NIDFANPKSF DLLQSTHTIC
     101  FNKRINTTNT KLNVETHTSS DIDNDILHVG APTDLGGNSN DEAETRQLRK
     151  FRWSNNKEKS LCEKLTVIYW ALLLHTTKRA SKRRPILCHQ MIAEFFNRVY
     201  KEKSRVPITS RYIRDNLVAW VTQGKELHEK GWVGDAKTGD LQEQFNIATV
     251  KLYESAEDGR LSIGKDKPFR EENTGSDSLV RAEEDSTAVT NENGHISSEK
     301  NLKKDRRESI RNQILTLDLN DEDFFQNVMK VLSAIDEPEL RQYVIVISEL
     351  VSMEMDDGKT VREKLRDVEL NINRLQVDIK EIKEMLVTLI NK*

external links for Srl2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Srl2p

1)	Desany BA, et al. (1998) Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev 12(18):2956-70
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41