MEF1/YLR069C Protein Information

Standard Name	Mef1p 1
Systematic Name	Ylr069cp
ORF Classification	Verified
Description	Mitochondrial elongation factor involved in translational elongation (1)
Name Description	Mitochondrial Elongation Factor 1

Experimental Data
Molecules/cell	6350 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	761
Molecular Weight (Da)	84,573
Isoelectric Point (pI)	6.83

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mef1p (InterPro)
Physical Interactions	There are 10 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000129CA6 \| P25039 MIPS: YLR069C NCBI: 1181289 \| 1360422 \| 3123209 \| 3918 \| 51013339 \| 6323098 \| NP_013170.1 GenBank/EMBL/DDBJ: DAA09386.1 \| AY692944 \| X58378 \| X94607 \| Z73241

Amino Acid Sequence (or in FASTA format)
1 MSVQKMMWVP RKMVGGRIPF FTCSKVFSGF SRRSFHESPL ARSTYEEEKV 51 LVDEIKQKLT PDDIGRCNKL RNIGISAHID SGKTTFTERV LYYTKRIKAI 101 HEVRGRDNVG AKMDSMDLER EKGITIQSAA TYCSWDKEGK NYHFNLIDTP 151 GHIDFTIEVE RALRVLDGAV LVVCAVSGVQ SQTVTVDRQM RRYNVPRVTF 201 INKMDRMGSD PFRAIEQLNS KLKIPAAAVQ IPIGSESSLS GVVDLINRVA 251 IYNKGDNGEI IEKGPVPENL KPLMEEKRQL LIETLADVDD EMAEMFLEEK 301 EPTTQQIKDA IRRSTIARSF TPVLMGSALA NTGIQPVLDA IVDYLPNPSE 351 VLNTALDVSN NEAKVNLVPA VQQPFVGLAF KLEEGKYGQL TYVRVYQGRL 401 RKGNYITNVK TGKKVKVARL VRMHSSEMED VDEVGSGEIC ATFGIDCASG 451 DTFTDGSVQY SMSSMYVPDA VVSLSITPNS KDASNFSKAL NRFQKEDPTF 501 RVKFDPESKE TIISGMGELH LEIYVERMRR EYNVDCVTGK PQVSYRESIT 551 IPADFDYTHK KQSGGAGQYG RVIGTLSPVD DITKGNIFET AIVGGRIPDK 601 YLAACGKGFE EVCEKGPLIG HRVLDVKMLI NDGAIHAVDS NELSFKTATM 651 SAFRDAFLRA QPVIMEPIMN VSVTSPNEFQ GNVIGLLNKL QAVIQDTENG 701 HDEFTLKAEC ALSTMFGFAT SLRASTQGKG EFSLEFSHYA PTAPHVQKEL 751 ISEFQKKQAK K*

Amino Acid Sequence (or in FASTA format)

       1  MSVQKMMWVP RKMVGGRIPF FTCSKVFSGF SRRSFHESPL ARSTYEEEKV
      51  LVDEIKQKLT PDDIGRCNKL RNIGISAHID SGKTTFTERV LYYTKRIKAI
     101  HEVRGRDNVG AKMDSMDLER EKGITIQSAA TYCSWDKEGK NYHFNLIDTP
     151  GHIDFTIEVE RALRVLDGAV LVVCAVSGVQ SQTVTVDRQM RRYNVPRVTF
     201  INKMDRMGSD PFRAIEQLNS KLKIPAAAVQ IPIGSESSLS GVVDLINRVA
     251  IYNKGDNGEI IEKGPVPENL KPLMEEKRQL LIETLADVDD EMAEMFLEEK
     301  EPTTQQIKDA IRRSTIARSF TPVLMGSALA NTGIQPVLDA IVDYLPNPSE
     351  VLNTALDVSN NEAKVNLVPA VQQPFVGLAF KLEEGKYGQL TYVRVYQGRL
     401  RKGNYITNVK TGKKVKVARL VRMHSSEMED VDEVGSGEIC ATFGIDCASG
     451  DTFTDGSVQY SMSSMYVPDA VVSLSITPNS KDASNFSKAL NRFQKEDPTF
     501  RVKFDPESKE TIISGMGELH LEIYVERMRR EYNVDCVTGK PQVSYRESIT
     551  IPADFDYTHK KQSGGAGQYG RVIGTLSPVD DITKGNIFET AIVGGRIPDK
     601  YLAACGKGFE EVCEKGPLIG HRVLDVKMLI NDGAIHAVDS NELSFKTATM
     651  SAFRDAFLRA QPVIMEPIMN VSVTSPNEFQ GNVIGLLNKL QAVIQDTENG
     701  HDEFTLKAEC ALSTMFGFAT SLRASTQGKG EFSLEFSHYA PTAPHVQKEL
     751  ISEFQKKQAK K*

external links for Mef1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Mef1p

1)	Vambutas A, et al. (1991) Mitochondrial translational-initiation and elongation factors in Saccharomyces cerevisiae. Eur J Biochem 201(3):643-52
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41