RPL22A/YLR061W Protein Information Help

Standard Name Rpl22ap
Systematic Name Ylr061wp
ORF Classification Verified
Description Ribosomal 60S subunit protein L22A; required for the oxidative stress response in yeast; homologous to mammalian ribosomal protein L22, no bacterial homolog; RPL22A has a paralog, RPL22B, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description Ribosomal Protein of the Large subunit
Gene Product L22A 1 , L22e 5 , YL31 1 , l1c 1 , rp4 1
Experimental Data
Molecules/cell 60400 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 121
Molecular Weight (Da) 13,693
Isoelectric Point (pI) 6.01

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rpl22ap (InterPro)
Physical Interactions There are 16 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000168396 | P05749
MIPS: YLR061W
NCBI: 1181282 | 1370303 | 1710538 | 315113318 | 365767271 | 365767313 | 410562499 | 6323090 | NP_013162.1
GenBank/EMBL/DDBJ: DAA09379.1 | X94607 | Z73233
Amino Acid Sequence (or in FASTA format)
 
       1  MAPNTSRKQK IAKTFTVDVS SPTENGVFDP ASYAKYLIDH IKVEGAVGNL
      51  GNAVTVTEDG TVVTVVSTAK FSGKYLKYLT KKYLKKNQLR DWIRFVSTKT
     101  NEYRLAFYQV TPEEDEEEDE E*

external links for Rpl22ap
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Rpl22ap
1) Planta RJ and Mager WH  (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
2) Lecompte O, et al.  (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Chan CT, et al.  (2012) Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nat Commun 3():937
5) Jenner L, et al.  (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41