RPL15A/YLR029C Protein Information

Standard Name	Rpl15ap
Systematic Name	Ylr029cp
Alias	Rpl10ap
ORF Classification	Verified
Description	Ribosomal 60S subunit protein L15A; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L15, no bacterial homolog; RPL15A has a paralog, RPL15B, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description	Ribosomal Protein of the Large subunit
Gene Product	L13A 2 , L15A 2 , L15e 5 , YL10 2 , rp15R 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	204
Molecular Weight (Da)	24,422
Isoelectric Point (pI)	11.96

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rpl15ap (InterPro)
Physical Interactions	There are 124 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000004F941 \| P05748 MIPS: YLR029C NCBI: 1360342 \| 287626 \| 315113313 \| 315113538 \| 315113585 \| 365767264 \| 365767306 \| 410562492 \| 49258850 \| 6323057 \| 730534 \| NP_013129.1 GenBank/EMBL/DDBJ: DAA09347.1 \| D14675 \| Z73201

Amino Acid Sequence (or in FASTA format)
1 MGAYKYLEEL QRKKQSDVLR FLQRVRVWEY RQKNVIHRAA RPTRPDKARR 51 LGYKAKQGFV IYRVRVRRGN RKRPVPKGAT YGKPTNQGVN ELKYQRSLRA 101 TAEERVGRRA ANLRVLNSYW VNQDSTYKYF EVILVDPQHK AIRRDARYNW 151 ICDPVHKHRE ARGLTATGKK SRGINKGHKF NNTKAGRRKT WKRQNTLSLW 201 RYRK*

Amino Acid Sequence (or in FASTA format)

       1  MGAYKYLEEL QRKKQSDVLR FLQRVRVWEY RQKNVIHRAA RPTRPDKARR
      51  LGYKAKQGFV IYRVRVRRGN RKRPVPKGAT YGKPTNQGVN ELKYQRSLRA
     101  TAEERVGRRA ANLRVLNSYW VNQDSTYKYF EVILVDPQHK AIRRDARYNW
     151  ICDPVHKHRE ARGLTATGKK SRGINKGHKF NNTKAGRRKT WKRQNTLSLW
     201  RYRK*

external links for Rpl15ap

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Rpl15ap

1)	Lee JC, et al. (1983) Binding of proteins from the large ribosomal subunits to 5.8 S rRNA of Saccharomyces cerevisiae. J Biol Chem 258(2):854-8
2)	Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
3)	Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
4)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5)	Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67