YCT1/YLL055W Protein Information

Standard Name	Yct1p 1
Systematic Name	Yll055wp
ORF Classification	Verified
Description	High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene (1, 2)
Name Description	Yeast Cysteine Transporter 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	531
Molecular Weight (Da)	58,904
Isoelectric Point (pI)	6.77

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yct1p (InterPro)
Transmembrane Domains	There are 10 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006B470 \| Q12235 MIPS: YLL055W NCBI: 1360260 \| 51012719 \| 6322973 \| 642329 \| 74676557 \| NP_013045.1 GenBank/EMBL/DDBJ: DAA09269.1 \| AY692634 \| Z47973 \| Z73160
External Classifications	TC: 2.A.1.14 [The Anion: Cation Symporter (ACS) Family]

Amino Acid Sequence (or in FASTA format)
1 MSKVDVKIGA DSISSSDEIL VPSRLADVTL AFMEENDAAV PEITPEQEKK 51 LKRKLFLTIF TFVSAINLLL YMDKATLSYD SILGFFEDTG LTQNTYNTVN 101 TLFYVGFAIG QFPGQYLAQK LPLGKFLGGL LATWTILIFL SCTAYNFSGV 151 VALRFFLGLT ESVVIPILIT TMGMFFDASE RAAAQPFFFA ACMGSPIPTG 201 FIAYGVLHIT NPSISLWKIF TIIIGGLTFI MTVVVILWFP NNPADVKFFS 251 IQERVWIIRR VQASTGSSIE QKVFKKSQFR EAMKDYITWL FGLFFLLQQL 301 ANNLPYQQNL LFEGMGGVDA LGSTLVSVAG AGFAVVCAFI ATLMLAKWKN 351 ISALTAIFWT LPALVGSIAA AALPWDNKIG ILANICMAGQ IFGIPFIIAL 401 SWASSSASGY TKKLTRSSVS LFAMGIANII SPQIWREKDS PRFLPAWIVQ 451 IVLSFSLAPA ILLLIHFILK RRNNQRLKNY DENLQNYLDR IQLIESENPS 501 SIEEGKVVTH ENNLAVFDLT DLENETFIYP L*

Amino Acid Sequence (or in FASTA format)

       1  MSKVDVKIGA DSISSSDEIL VPSRLADVTL AFMEENDAAV PEITPEQEKK
      51  LKRKLFLTIF TFVSAINLLL YMDKATLSYD SILGFFEDTG LTQNTYNTVN
     101  TLFYVGFAIG QFPGQYLAQK LPLGKFLGGL LATWTILIFL SCTAYNFSGV
     151  VALRFFLGLT ESVVIPILIT TMGMFFDASE RAAAQPFFFA ACMGSPIPTG
     201  FIAYGVLHIT NPSISLWKIF TIIIGGLTFI MTVVVILWFP NNPADVKFFS
     251  IQERVWIIRR VQASTGSSIE QKVFKKSQFR EAMKDYITWL FGLFFLLQQL
     301  ANNLPYQQNL LFEGMGGVDA LGSTLVSVAG AGFAVVCAFI ATLMLAKWKN
     351  ISALTAIFWT LPALVGSIAA AALPWDNKIG ILANICMAGQ IFGIPFIIAL
     401  SWASSSASGY TKKLTRSSVS LFAMGIANII SPQIWREKDS PRFLPAWIVQ
     451  IVLSFSLAPA ILLLIHFILK RRNNQRLKNY DENLQNYLDR IQLIESENPS
     501  SIEEGKVVTH ENNLAVFDLT DLENETFIYP L*

external links for Yct1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	TCDB
	GeneMANIA	YeastRC Structure Prediction (Seattle)

References cited on this page View Complete Literature Guide for Yct1p

1)	Kaur J and Bachhawat AK (2007) Yct1p, a Novel, High-Affinity, Cysteine-Specific Transporter From the Yeast Saccharomyces cerevisiae. Genetics 176(2):877-90
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91