RIX7/YLL034C Protein Information

Standard Name	Rix7p
Systematic Name	Yll034cp
ORF Classification	Verified
Description	Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions (1)
Name Description	RIbosome eXport 1

Experimental Data
Molecules/cell	4490 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	837
Molecular Weight (Da)	93,068
Isoelectric Point (pI)	5.11

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rix7p (InterPro)
Physical Interactions	There are 83 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000053235 \| Q07844 MIPS: YLL034C NCBI: 1360222 \| 2492526 \| 6322994 \| NP_013066.1 GenBank/EMBL/DDBJ: DAA09287.1 \| Z73139

Amino Acid Sequence (or in FASTA format)
1 MVKVKSKKNS LTSSLDNKIV DLIYRLLEEK TLDRKRSLRQ ESQGEEGENN 51 EGEEDEDIFE SMFFAKDLTA GEIFTFCLTK DLSLQRVKKV VLQKTIDRML 101 KDVIESELEE FGSYPGYNNE EEEKPSLEEE LAKKNMMIER DTNEMNKRIT 151 STWSKSGSVS ESITETDDPK TEEVKKSKKR SKEGTCKVKR QKIKEDRSPP 201 NSSLKSLGGM DDVVAQLMEL IGLPILHPEI FLSTGVEPPR GVLLHGPPGC 251 GKTSIANALA GELQVPFISI SAPSVVSGMS GESEKKIRDL FDEARSLAPC 301 LVFFDEIDAI TPKRDGGAQR EMERRIVAQL LTSMDELTME KTNGKPVIII 351 GATNRPDSLD AALRRAGRFD REICLNVPNE VSRLHILKKM SDNLKIDGAI 401 DFAKLAKLTP GFVGADLKAL VTAAGTCAIK RIFQTYANIK STPTTATDSS 451 EDNMEIDETA NGDESSLKNT ANMIDPLPLS VVQQFIRNYP EPLSGEQLSL 501 LSIKYEDFLK ALPTIQPTAK REGFATVPDV TWANVGALQR VRLELNMAIV 551 QPIKRPELYE KVGISAPGGV LLWGPPGCGK TLLAKAVANE SRANFISIKG 601 PELLNKYVGE SERSIRQVFT RARASVPCVI FFDELDALVP RRDTSLSESS 651 SRVVNTLLTE LDGLNDRRGI FVIGATNRPD MIDPAMLRPG RLDKSLFIEL 701 PNTEEKLDII KTLTKSHGTP LSSDVDFEEI IRNEKCNNFS GADLAALVRE 751 SSVLALKRKF FQSEEIQSVL DNDLDKEFED LSVGVSGEEI IVTMSDFRSA 801 LRKIKPSVSD KDRLKYDRLN KKMGLTEEMK DAEEMKQ*

Amino Acid Sequence (or in FASTA format)

       1  MVKVKSKKNS LTSSLDNKIV DLIYRLLEEK TLDRKRSLRQ ESQGEEGENN
      51  EGEEDEDIFE SMFFAKDLTA GEIFTFCLTK DLSLQRVKKV VLQKTIDRML
     101  KDVIESELEE FGSYPGYNNE EEEKPSLEEE LAKKNMMIER DTNEMNKRIT
     151  STWSKSGSVS ESITETDDPK TEEVKKSKKR SKEGTCKVKR QKIKEDRSPP
     201  NSSLKSLGGM DDVVAQLMEL IGLPILHPEI FLSTGVEPPR GVLLHGPPGC
     251  GKTSIANALA GELQVPFISI SAPSVVSGMS GESEKKIRDL FDEARSLAPC
     301  LVFFDEIDAI TPKRDGGAQR EMERRIVAQL LTSMDELTME KTNGKPVIII
     351  GATNRPDSLD AALRRAGRFD REICLNVPNE VSRLHILKKM SDNLKIDGAI
     401  DFAKLAKLTP GFVGADLKAL VTAAGTCAIK RIFQTYANIK STPTTATDSS
     451  EDNMEIDETA NGDESSLKNT ANMIDPLPLS VVQQFIRNYP EPLSGEQLSL
     501  LSIKYEDFLK ALPTIQPTAK REGFATVPDV TWANVGALQR VRLELNMAIV
     551  QPIKRPELYE KVGISAPGGV LLWGPPGCGK TLLAKAVANE SRANFISIKG
     601  PELLNKYVGE SERSIRQVFT RARASVPCVI FFDELDALVP RRDTSLSESS
     651  SRVVNTLLTE LDGLNDRRGI FVIGATNRPD MIDPAMLRPG RLDKSLFIEL
     701  PNTEEKLDII KTLTKSHGTP LSSDVDFEEI IRNEKCNNFS GADLAALVRE
     751  SSVLALKRKF FQSEEIQSVL DNDLDKEFED LSVGVSGEEI IVTMSDFRSA
     801  LRKIKPSVSD KDRLKYDRLN KKMGLTEEMK DAEEMKQ*

external links for Rix7p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Mass Spec (Seattle)
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rix7p

1)	Gadal O, et al. (2001) A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits. EMBO J 20(14):3695-704
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41