COX17/YLL009C Protein Information 
| Standard Name | Cox17p |
|---|---|
| Systematic Name | Yll009cp |
| ORF Classification | Verified |
| Description | Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs (1, 2, 3, 4, 5) |
| Name Description | Cytochrome c OXidase |
| Click on image for expanded interactive view |
|---|
| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Cox17p (InterPro) |
| Physical Interactions | There are 15 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI0000168392 | Q12287 MIPS: YLL009C NCBI: 1163003 | 1360173 | 2493874 | 55670290 | 55670291 | 6323020 | 71042150 | NP_013092.1 GenBank/EMBL/DDBJ: DAA09309.1 | L75948 | Z73114 |
external links for Cox17p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | Organelle DB |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YPL+ |
| Aspergillus (AspGD) | BioPIXIE | MIPS | YeastGFP |
| Candida (CGD) | CYC2008 (complexes) | Pfam domains | YeastRC Public Image Repository |
| Candida (CandidaDB) | Complexome | ||
| YGOB | DIP | ||
| YOGY | GeneMANIA | ||
| YeastRC Two-Hybrid (Seattle) |
References cited on this page View Complete Literature Guide for Cox17p
| 1) | Beers J, et al. (1997) Purification, characterization, and localization of yeast Cox17p, a mitochondrial copper shuttle. J Biol Chem 272(52):33191-6 |
| 2) | Heaton D, et al. (2000) Mutational analysis of the mitochondrial copper metallochaperone Cox17. J Biol Chem 275(48):37582-7 |
| 3) | Maxfield AB, et al. (2004) Cox17 is functional when tethered to the mitochondrial inner membrane. J Biol Chem 279(7):5072-80 |
| 4) | Horng YC, et al. (2004) Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. J Biol Chem 279(34):35334-40 |
| 5) | Longen S, et al. (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68 |
