SOR1/YJR159W Protein Information

Standard Name	Sor1p 1
Systematic Name	Yjr159wp
Alias	Sdh1p 2
ORF Classification	Verified
Description	Sorbitol dehydrogenase; expression is induced in the presence of sorbitol or xylose (2, 3)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	357
Molecular Weight (Da)	38,165
Isoelectric Point (pI)	6.92

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Sor1p (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001293A7 \| P35497 MIPS: YJR159W NCBI: 1015919 \| 295661 \| 51013475 \| 544159 \| 6322619 \| NP_012693.1 GenBank/EMBL/DDBJ: DAA08943.1 \| AY693012 \| L11039 \| Z49659
External Classifications	EC: 1.1.1.14 [L-iditol 2-dehydrogenase]

Amino Acid Sequence (or in FASTA format)
1 MSQNSNPAVV LEKVGDIAIE QRPIPTIKDP HYVKLAIKAT GICGSDIHYY 51 RSGGIGKYIL KAPMVLGHES SGQVVEVGDA VTRVKVGDRV AIEPGVPSRY 101 SDETKEGRYN LCPHMAFAAT PPIDGTLVKY YLSPEDFLVK LPEGVSYEEG 151 ACVEPLSVGV HSNKLAGVRF GTKVVVFGAG PVGLLTGAVA RAFGATDVIF 201 VDVFDNKLQR AKDFGATNTF NSSQFSTDKA QDLADGVQKL LGGNHADVVF 251 ECSGADVCID AAVKTTKVGG TMVQVGMGKN YTNFPIAEVS GKEMKLIGCF 301 RYSFGDYRDA VNLVATGKVN VKPLITHKFK FEDAAKAYDY NIAHGGEVVK 351 TIIFGPE*

Amino Acid Sequence (or in FASTA format)

       1  MSQNSNPAVV LEKVGDIAIE QRPIPTIKDP HYVKLAIKAT GICGSDIHYY
      51  RSGGIGKYIL KAPMVLGHES SGQVVEVGDA VTRVKVGDRV AIEPGVPSRY
     101  SDETKEGRYN LCPHMAFAAT PPIDGTLVKY YLSPEDFLVK LPEGVSYEEG
     151  ACVEPLSVGV HSNKLAGVRF GTKVVVFGAG PVGLLTGAVA RAFGATDVIF
     201  VDVFDNKLQR AKDFGATNTF NSSQFSTDKA QDLADGVQKL LGGNHADVVF
     251  ECSGADVCID AAVKTTKVGG TMVQVGMGKN YTNFPIAEVS GKEMKLIGCF
     301  RYSFGDYRDA VNLVATGKVN VKPLITHKFK FEDAAKAYDY NIAHGGEVVK
     351  TIIFGPE*

external links for Sor1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Sor1p

1)	McGonigal T, et al. (1998) Construction of a sorbitol-based vector for expression of heterologous proteins in Saccharomyces cerevisiae. Appl Environ Microbiol 64(2):793-4
2)	Sarthy AV, et al. (1994) Cloning and sequence determination of the gene encoding sorbitol dehydrogenase from Saccharomyces cerevisiae. Gene 140(1):121-6
3)	Toivari MH, et al. (2004) Endogenous xylose pathway in Saccharomyces cerevisiae. Appl Environ Microbiol 70(6):3681-6